Optimizing Adeno-Associated Virus Loading Amounts for Host Cell Protein Analysis

Application Note Biopharma/Pharma Adeno-Associated Virus Characterization with Agilent 6545XT AdvanceBio LC/Q-TOF and Protein Metrics Byos Software Authors Wendi A. Hale and Christopher M. Colangelo Agilent Technologies Inc. Lexington, MA, USA Michelle English Protein Metrics Cupertino, CA, USA Abstract This application…

Consumables Workflow Ordering Guide Host Cell Protein Analysis by RP-LC/MS Unlike small molecules and oligos, mAbs and other protein-based therapeutics, including adeno-associated virus (AAV) capsids are engineered and produced using a cell line. These cell lines include CHO (Chinese Hamster…

Poster Reprint ASMS 2021 Poster number WP259 Comprehensive Adeno-Associated Virus Critical Quality Attribute Analysis with Liquid Chromatography-Mass Spectrometry Wendi A. Hale1, Michelle English2, Lawrie Veale2, St John Skilton2, Christopher M. Colangelo1 1Agilent, Lexington, MA 2Protein Metrics, Cupertino, CA Introduction Adeno-associated…

Application Note Biotherapeutics and Biosimilars Host Cell Protein Analysis Using Agilent AssayMAP Bravo and 6545XT AdvanceBio LC/Q-TOF Authors Linfeng Wu, Shuai Wu and Te-Wei Chu Agilent Technologies, Inc., Santa Clara, CA, USA Introduction Use of biopharmaceuticals such as monoclonal antibodies…