Jnana Therapeutics: Rapid Target Identification in Drug Discovery

High-Throughput Lead Discovery with Agilent RapidFire/MS Systems: Analysis of Stearoyl-Coenzyme A Desaturase (SCD) Application Note Authors Introduction William Lamarr, Lauren Frick, and Peter Rye Agilent Technologies, Inc. Wakefield, MA USA The RapidFire High-throughput Mass Spectrometry System provides drug discovery researchers…

RapidFire for Automated High-Throughput LC/MS Proven. Rapid. Complete. Application Compendium Table of Contents Introduction3 Application Notes Method Development High-Throughput (Sub-2.5 Second) Direct Injection Analysis by  Mass Spectrometry 4 Automated Method Development Using the Agilent RapidFire  High-Throughput Mass Spectrometry…

Application Note Drug Discovery Ultrafast Analysis of Metabolic Stability Assays Using Agilent RapidFire High-Resolution MS Authors Michelle V. Romm, Nikunj Parikh, and Vaughn P. Miller Agilent Technologies, Inc. Wakefield, MA Yuqin Dai Agilent Technologies, Inc. Santa Clara, CA Abstract The…

Application Note Pharma and Biopharma High-Throughput In Vitro ADME Analysis with Agilent RapidFire/MS Systems: Permeability Assays Author Vaughn MillerAgilent Technologies, Inc. Introduction During the drug discovery process, permeability assays such as Caco-2 (cell line) and PAMPA (parallel artificial membrane permeation…