IMPROVED BIOPHARMACEUTICAL PEPTIDE MAPPING WORKFLOWS USING A NOVEL AUTOLYSIS-RESISTANT TRYPSIN ENZYME Samantha Ippoliti1, Nick Zampa1, Ying Qing Yu1, Matthew A Lauber1, Leslie Napoletano1, Scott Berger1 Waters Corporation, Milford, MA METHODS Peptide mapping provides a wealth of information about a protein…
Klíčová slova
trypsin, autolysis, rapizyme, mapping, overnight, peptide, digestion, missed, competitor, cleavage, trypsins, accelerated, rapizymetm, resistant, protocols