Analysis of Paromomycin by HPAE-IPAD

Application Note 186 Analysis of Paromomycin by HPAE-IPAD INTRODUCTION Paromomycin (Figure 1) is an aminoglycoside antibiotic produced by Streptomyces rimosus var. paromomycinus.1 The antibacterial spectrum of paromomycin is similar to other aminoglycosides that demonstrate broad spectrum activity against some gram-positive…

Application Note 190 Determination of Sulfate Counter Ion and Anionic Impurities in Aminoglycoside Drug Substances by Ion Chromatography with Suppressed Conductivity Detection INTRODUCTION Most drug substances are produced synthetically in bulk and formulated into convenient dosage forms, such as tablets,…

Application Note 190 Determination of Sulfate Counter Ion and Anionic Impurities in Aminoglycoside Drug Substances by Ion Chromatography with Suppressed Conductivity Detection INTRODUCTION Most drug substances are produced synthetically in bulk and formulated into convenient dosage forms, such as tablets,…

Application Note 66 Determination of Neomycin B and Impurities Using HPAE-IPAD INTRODUCTION Neomycin is a complex of water-soluble aminoglycoside antibiotics purified from the fermentation of the actinomycete Streptomyces fradiae and used in a variety of pharmaceutical applications, including topical, ophthalmic,…