Fluoropolymer Bottle Extractables Profile

Savillex Technical Note PurillexTM PFA and FEP Bottles - Extractables Testing Overview Fluoropolymer (PFA and FEP) bottles are widely used in the pharmaceutical industry process stream for the storage and transfer of pharmaceutical intermediates including API (active pharmaceutical ingredient). They…

Savillex Technical Note CO2 Transmission Into Bulk Drug Substance Containers Summary Ingress of carbon dioxide into bulk drug substance (BDS) containers that are stored and shipped on dry ice is a serious and often understated problem. Although all bag systems…

Savillex Technical Note Freeze Drop Testing of Bulk Drug Substance Bottles Summary Frozen storage of bulk drug substance (BDS) at temperatures at or below -70°C is common in the bioprocess industry. Storage at temperatures below -80°C can lead to spontaneous…

Savillex Technical Note Flash Freezing in Fluoropolymer Bottles Summary Flash freezing is the process of rapidly lowering the temperature of a liquid so that larger ice crystals do not have the chance to form. These larger crystals can potentially damage…