Freeze Drop Testing of Bulk Drug Substance Bottles

Savillex Technical Note Freeze Cycle Testing Summary Storing frozen bulk drug substances (BDS) – including bioprocess solutions, vaccines, blood components, and other delicate process fluids – is common practice in the bioprocess industry. Vessels used to store these fluids must…

Savillex Technical Note Freeze Mapping - Savillex Fluoropolymer Bottles Summary The ability to freeze bulk drug substance (BDS) at temperatures at or below -80°C is critical to the bioprocess industry – as are rapid and efficient freezing and thawing processes.…

Savillex Technical Note Flash Freezing in Fluoropolymer Bottles Summary Flash freezing is the process of rapidly lowering the temperature of a liquid so that larger ice crystals do not have the chance to form. These larger crystals can potentially damage…

Savillex Technical Note CO2 Transmission Into Bulk Drug Substance Containers Summary Ingress of carbon dioxide into bulk drug substance (BDS) containers that are stored and shipped on dry ice is a serious and often understated problem. Although all bag systems…