Structural Elucidation of Unknown Impurities in the Kinase Inhibitor Imatinib Using UHPLC and High-Resolution Mass Spectrometry

Application Note Modernized Impurity Analysis of the Kinase Inhibitor Imatinib by High-Resolution LC With MS-Compatible Mobile Phases Peng Chen, Bonnie A. Alden, Matthew A. Lauber Waters Corporation Abstract A UPLC method has been developed with a charged surface phenyl stationary…

Extractables, Leachables, and Food Contact Materials Application Notebook Extractables, Leachables, and Food Contact Materials Testing The safety of pharmaceuticals, cosmetics, and foodstuffs may be compromised by chemical compounds in the various types of packaging and food contact materials (FCMs) that…

Characterization of Impurities in the Fungicide Flutriafol Using UNIFI and UPLC-ToF-MS E Marian Twohig, Michael O’Leary, Peter Lee, and John McCauley Waters Corporation, Milford, MA, USA A P P L I C AT I O N B E N E…

A Workflow Approach for the Identification and Structural Elucidation of Impurities of Quetiapine Hemifumarate Drug Substance Michael D. Jones, Marian Twohig, Karen Haas, and Robert S. Plumb Waters Corporation, Milford, MA, USA INT RODUC T ION The ability to understand…