1D/2D-UHPLC-MS System and its use in the Field of Drug Metabolism and Pharmacokinetics

The incentive of dual injection capabilities for method development and quantitation in heart-cut 2D-LC Chris Tuczemskyi, Matthias Schiell, Maria Grübner, Frank Steiner The world leader in serving science 1 [email protected] | September 2022 Application-specific LC systems …multiple dependent or independent…

APPLICATION NOTE 73351 Simultaneous determination of vitamin A, D and four vitamin E isomers in infant formula by offline solid phase extraction and online two-dimensional liquid chromatography Authors: Guobin Shen1, Yan Jin1, Giorgia Greco2, Dennis Koehler2, Sabrina Patzelt2 Thermo Fisher…

TECHNICAL NOTE 73298 Flexible HPLC instrument setups for double usage as one heart-cut-2D-LC system or two independent 1D-LC systems Authors: Maria Grübner and Giorgia Greco Thermo Fisher Scientific, Germering, Germany Keywords: Two-dimensional liquid chromatography, 2D-LC, 2D-HPLC, heart-cut-2D-LC, Vanquish Duo UHPLC…

Application note | 004276 Biopharma Monitoring monoclonal antibody bioproduction processes with 2D-LC-UV Author Application benefits Maria Grübner, Thermo Fisher Scientific, • Heart-cut 2D-LC with protein A affinity chromatography (ProA) of cell culture samples enables titer determination and purification for subsequent…