Identification of metabolites in human plasma using GC-Orbitrap-MS after online derivatization

Fully Automated Online Trimethylsilyl (TMS) Derivatization Protocol for Metabolite Profiling Using an Orbitrap GC-MS and High Resolution Accurate Mass Metabolomics Library Xin Zheng1, Giulia Riccardino2, Jason Cole1, Paul Silcock3 1Thermo Fisher Scientific, Austin, Texas; 2Thermo Fisher Scientific, Runcorn, Cheshire INTRODUCTION…

Understanding Synthetic Biology using the Q Exactive GC Orbitrap GC-MS and a High Resolution Accurate Mass Metabolomics Library for Untargeted Metabolomics Cristian Cojocariu1, Maria Vinaxia2, Mark Dunstan2, Adrian J. Jervis2, Paul Silcock1 and Nicholas J. W. Rattray2 Fisher Scientific, Runcorn,…

Stefan Weidt,2 Bogusia Pesko,2 Cristian Cojocariu,1 Paul Silcock,1 Richard J. Burchmore,2 and Karl Burgess2 Thermo Fisher Scientific, Runcorn, UK 2 Glasgow Polyomics, University of Glasgow, Glasgow, UK 1 Ap plica t ion Note 1 045 7 Untargeted Metabolomics Using Orbitrap-Based…

Back to the Future with Thermo Scientific™ Q Exactive™ GC Orbitrap™ GC-MS/MS 1 Proprietary & Confidential The world leader in serving science 2 1 Why GC/MS for Metabolomics? 2 Why High Resolution/Accurate Mass (HRAM) GC/MS for Metabolomics? 3 Tools for…