APPS: Method for the Analysis and Quantitation of Pharmaceutical Counterions Utilizing Hydrophilic Interaction Liquid Chromatography

METHOD FOR THE ANALYSIS AND QUANTITATION OF PHARMACEUTICAL COUNTERIONS UTILIZING HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHY Brianna Clements, Margaret Maziarz, Evelien Dejaegere*, Paul Rainville Waters Corporation, 34 Maple Street, Milford MA, 01757, USA *Corresponding author: [email protected]: Waters NV/SA, The ultimate building -…

Application Note Method for the Analysis and Quantitation of Pharmaceutical Counterions Utilizing Hydrophilic Interaction Liquid Chromatography Brianna R Clements, Margaret Maziarz, Paul D. Rainville Waters Corporation Abstract Hydrophilic Interaction Liquid Chromatography (HILIC) combined with Evaporative Light Scattering Detector (ELSD) enables…

Application Note Quantification of Inorganic Counterions Using Hydrophilic Liquid Chromatography Coupled with Charged Aerosol Detection (CAD) Margaret Maziarz, Stephanie Harden, Paul Rainville Waters Corporation, United States Published on July 16, 2026 Abstract Analysis of counterions during pharmaceutical development is critical…

Application Note Analysis of Metformin and its Impurities Using Hydrophilic Interaction Liquid Chromatography (HILIC) Coupled With Ultraviolet (UV) and Mass Spectrometry (MS) Detection Brianna R Clements, Paul D. Rainville Waters Corporation Abstract Diabetes is a leading cause of death in…