SCF 527 Precipitation of Protein Powders into a Compressed Antisolvent lyophilization, and using miscible organic antisolvents. Unfortunately, these processes can also inactivate or denature proteins, produce small final yields, lead to electrostatically charged powders, produce particles with a broad distribution,…
Klíčová slova
antisolvent, supercritical, protein, microparticulate, pca, systems, compressed, powders, implantable, precipitation, size, administering, release, particles, injectable
