The Impact of Methanol on Hydrophilic Interaction Liquid Chromatography (HILIC) Retention Mechanisms – A Systematic Approach

Toward Green and Sustainable Hydrophilic Interaction Liquid Chromatography (HILIC) Workflows: Can We Replace Acetonitrile? Are There Alternative Modes? David S. Bell*1, Jan Pschierer2 and Sandra Ruiz Perez2 1Restek Corporation 110 Benner Circle, Bellefonte, PA, USA 16823 2 Restek GmbH, Schaberweg…

Retention and Selectivity in Aqueous Normal Phase/HILIC Separations David S. Bell Supelco, Div. of Sigma-Aldrich, Bellefonte, PA 16823 USA www.sigma-aldrich.com T410093 Abstract Interest in chromatography using aqueous-organic mobile phases high in organic content (aqueous normal-phase, ANP, HILIC) has continued to…

Stability and Performance of Cyano Bonded Phase HPLC Columns for Reversed-Phase, Normal-Phase and HILIC Applications Richard A. Henry, Carmen T. Santasania, William H. Campbell and Wendy Roe sigma-aldrich.com T410171 Fundamentals of Ascentis® ES Cyano R. A. Henry EAS 2010 2…

Thermo Scientific HILIC Separations Technical Guide HILIC Separations A Practical Guide to HILIC Mechanisms, Method Development and Troubleshooting Table of Contents Introduction . . . . . . . . . …