Retention and Selectivity in Aqueous Normal Phase/HILIC Separations

The Impact of Methanol on Hydrophilic Interaction Liquid Chromatography (HILIC) Retention Mechanisms – A Systematic Approach David S. Bell HPLC 2022 Symposium, San Diego, CA Outline Quick HILIC system review Choice of organic solvents Systematic investigation of methanol incorporation and…

Thermo Scientific HILIC Separations Technical Guide HILIC Separations A Practical Guide to HILIC Mechanisms, Method Development and Troubleshooting Table of Contents Introduction . . . . . . . . . …

High Throughput Bioanalysis Utilizing Fused-Core Particle and HybridSPE -PPT Technology ™ ® Craig R. Aurand, Hillel K. Brandes, Dave S. Bell, Wayne Way, Carmen T. Santasania, and Daniel Vitkuske Supelco, Div. of Sigma-Aldrich, Bellefonte, PA 16823 USA www.sigma-aldrich.com T410086 Introduction…

Troubleshooting Liquid Chromatographic Separations: Avoiding Common Issues through Informed Method Development Practices Dave S. Bell Supelco, Div. of Sigma-Aldrich Bellefonte, PA 16823 USA sigma-aldrich.com/analytical T414096 © 2014 Sigma-Aldrich Co. All rights reserved. Objective •Most of the difficult problems encountered are…