Dynamic Binding Capacity and High‑Resolution Oligonucleotide Analysis with Agilent Bio SAX Columns

Oligonucleotide Analysis: Practical Techniques and Method Development Optimization for HPLC Mohit Patel LC Columns and Consumables Technical Support December 19, 2023 1 12/19/2023 DE # DE48216954 What Are Oligonucleotide Therapeutic Types? Oligonucleotides are being increasingly developed as therapeutics against a…

Technical Overview Dynamic Binding Capacity of Oligonucleotides on PLRP-S Columns and Stationary Phases Author Dr. Andrew Coffey Agilent Technologies, Inc. Abstract PLRP-S is a polymeric polystyrene/divinylbenzene (PS/DVB) reversed-phase material that is ideally suited to oligonucleotide separation and purification, and is…

Oligonucleotide Purification Solutions Agilent PLRP-S and PL-SAX HPLC columns R + + R + R R + PL-SAX 1000 Å Pore Size 1000 Å PLRP-S 1000 Å Pore Size 1000 Å It’s All About Scalability Whether you’re working on the…

Application Note Biopharmaceuticals Analysis of Oligonucleotides with Ion Exchange Chromatography and Agilent Infinity II UHPLC Authors Abstract Chae-Young Ryu and Brian Liau Agilent Technologies, Inc. Although oligonucleotide analysis is frequently conducted using ion-pair reversed‑phase chromatography, ion exchange chromatography can be…