Accelerating proteotyping transformation into clinical routine via an intelligent data acquisition Hybrid-DIA MS based proteomics solution

Combining the Data-driven and Hypothesis-driven Approaches in One Go via a Novel Intelligent Data Acquisition Hybrid-DIA Mass Spectrometry Strategy Yue Xuan1, Min Huang2, Xiangyun Yang2, Kyle Fort1, Jesse D. Canterbury3, Daniel Lopez Ferrer3, Tao Bo2, Alexander Makarov1, Andreas F. Huhmer3…

An intelligent Hybrid-DIA data acquisition strategy for cracking the clinical sample complexity challenge in translational proteotyping Sandra Goetze1,2, Kyle Fort3, Jesse D. Canterbury4, Audrey van Drogen1,2, Alexander Makarov3, Bernd Wollscheid1,2, Yue Xuan3 1 Swiss Federal Institute of Technology Zurich (ETHZ),…

Technical note | 004116 Omics Hybrid DIA on the Orbitrap Excedion Pro mass spectrometer: Bridging global depth and targeted sensitivity for proteomic analysis Authors Goal Patience Sanderson, Katherine To develop and evaluate the performance of hybrid data-independent acquisition (hybrid Walker,…

Technical note | 004324 Proteomics Unveil plasma proteomics with cutting-edge hybrid-DIA methods utilizing two strategies on the Orbitrap Astral Zoom MS Authors Goal Qingling Li¹, Jared Deyarmin¹, Sophia Develop and evaluate hybrid-DIA methods utilizing two strategies to simultaneously Steigerwald², Stephanie…