Combining the Data-driven and Hypothesis-driven Approaches in One Go via a Novel Intelligent Data Acquisition Hybrid-DIA Mass Spectrometry Strategy

Accelerating proteotyping transformation into clinical routine via an intelligent data acquisition Hybrid-DIA MS based proteomics solution Yue Xuan1, Sandra Goetze2-4, Audrey van Drogen2-4, Patrick G.A. Pedrioli2-4, Ana Martínez-Val5, Jesse D. Canterbury6, Kyle Fort1, Daniel Lopez Ferrer6, Andreas F. Huhmer6, Jesper…

An intelligent Hybrid-DIA data acquisition strategy for cracking the clinical sample complexity challenge in translational proteotyping Sandra Goetze1,2, Kyle Fort3, Jesse D. Canterbury4, Audrey van Drogen1,2, Alexander Makarov3, Bernd Wollscheid1,2, Yue Xuan3 1 Swiss Federal Institute of Technology Zurich (ETHZ),…

WHITE PAPER 65659 Grant application resource: Using the Orbitrap Exploris 480 mass spectrometer to accelerate fundamental research Keywords: Single Cell Sensitivity, TMT & TMTpro Multiplexing, SureQuant Method, Quantitative Proteomics, Orbitrap Exploris 480 MS, FAIMS Pro interface, Mass Spectrometry Goal This…

Technical note | 004324 Proteomics Unveil plasma proteomics with cutting-edge hybrid-DIA methods utilizing two strategies on the Orbitrap Astral Zoom MS Authors Goal Qingling Li¹, Jared Deyarmin¹, Sophia Develop and evaluate hybrid-DIA methods utilizing two strategies to simultaneously Steigerwald², Stephanie…