SPATIAL DISTRIBUTION AND IDENTIFICATION OF PROTEIN IN TUBERCULOSIS GRANULOMAS USING DESI AND CYCLIC ION MOBILITY

DESITM Cyclic IMS Enables the Detection and Spatial Distribution of Proteins in Tuberculosis Granulomas Hernando Olivos1; Emmanuelle Claude2; Veronique Dartois3; Ning Wang3; Claire Carter3 1Waters Corporation Milford, MA; 2Waters Corporation, Wilmslow, UK; 3Center for Discovery and Innovation, Nutley, NJ Introduction…

[ APPLICATION NOTEBOOK ] MS IMAGING AND AMBIENT IONIZATION-MS FOR METABOLOMICS AND LIPIDOMICS 1 This notebook is an excerpt from the larger Waters’ Application Notebook on Metabolomics and Lipidomics #720005245EN TABLE OF CONTENTS 3 Introduction 4 Biomarker Discovery Directly from…

Waters Cyclic IMS P20 Mass Spectrometer Insight—revealed, not inferred. Insight— revealed, not inferred Biological systems are inherently complex, and answering today’s research questions requires tools that can reveal that complexity with clarity. The Waters™ Cyclic™ IMS P20 Mass Spectrometer enables…

EVALUATION OF DESI MOUNTED ON Q-TOF AND TQ MASS SPECTROMETERS TO IMAGE PFAS COMPOUNDS IN DIFFERENT MATRICES Emmanuelle Claude, Alexandra Lee, Mujeebatu Kadiri-Asamoah, Stuart Adams, Emrys Jones, Joanne Ballantyne Waters Corporation, Wilmslow, UK INTRODUCTION Per- and polyfluoroalkyl substances (PFAS) are…