An Integrated Workflow for the Analysis of Oligonucleotides and Their Impurities by Agilent High-Resolution LC/(Q-)TOF Mass Spectrometry

Application Note Pharma & Biopharma Oligonucleotides Oligonucleotide Characterization by Agilent 1290 Infinity II Bio LC and 6545XT AdvanceBio LC/Q-TOF Oligonucleotide identity, impurities analysis and sequence determination using BioConfirm 12.0 target plus impurities (TPI) and sequence confirmation workflows Authors Introduction Bian…

Application Note Biopharma/Pharma Comprehensive and Integrated Workflow for Oligonucleotide Sequence Confirmation by Agilent High-Resolution LC/Q-TOF Robust and sensitive sequence confirmation of synthetic oligonucleotides and impurities Authors David L. Wong and Peter Rye Agilent Technologies, Inc. Abstract This application note demonstrates…

Poster Reprint ASMS 2023 Poster number ThP 566 Oligonucleotide Characterization by Bio LC and Q-TOF Yulan Bian1, David L Wong2 1Agilent Technologies, Inc., Singapore 2Agilent Technologies, Inc., Santa Clara, CA Introduction Experimental Sample preparation Oligonucleotide (RNA) Resolution Standard was obtained…

Poster Reprint ASMS 2022 Poster number WP386 Comprehensive, Automated, and Integrated Software for Oligonucleotide Characterization and Sequence Confirmation David Wong1; Peter Rye2; Stephen Madden1; Gordon Slysz1 and Crystal Cody1 1Agilent Technologies, Inc., Santa Clara, CA 2Agilent Technologies, Inc., Lexington, MA…