Low Attomole Limit of Quantification on an Orbitrap Fusion Lumos Tribrid Mass Spectrometer

Reiko Kiyonami, Michael Senko, Vlad Zabrouskov, Andreas F.R. Hühmer, Thermo Fisher Scientific, San Jose, CA, USA Jarrett Egertson, Sonia Ting, Michael MacCoss, University of Washington, Seattle, WA, USA Appli cat i on N ote 6 0 0 Large-Scale Targeted Protein…

The Most Powerful Instrument DESIGNED TO ADVANCE YOUR SCIENTIFIC PURSUITS Thermo Scientific Orbitrap Fusion Lumos Tribrid Mass Spectrometer PUSHING NEW FRONTIERS IN SCIENCE Breakthroughs in science rely on great scientists making rapid progress answering challenging questions. “How does lipid metabolism…

Large Scale Targeted Protein Quantification Using WiSIM-DIA Workflow on a Orbitrap Fusion Tribrid Mass Spectrometer Reiko Kiyonami,1 Bhavin Patel, 3 Michael Senko,1 Vlad Zabrouskov,1 Jarrett Egertson, 2 Sonia Ting, 2 Michael MacCoss, 2 John Rogers, 3 Andreas FR Hühmer1 1…

Methods A F e d 2 p l Sample Preparation Before committing valuable sample, instrument performance was verified using a standard Pierce HeLa cell digest with Biognosys HRM kit spiked in 1:10 according to the manufacturer’s instructions. Next, two non-small…