Analysis of Full/Empty Capsid Ratios in Adeno-Associated Virus 1 and 6 Serotypes Using Biocompatible Liquid Chromatography

Poster Reprint ASMS 2022 Poster number MP474 Analysis of Adeno-Associated Virus Quality Attributes with LC-FLD-(MS) Brian Liau, Matthew L. Turner, Wendi Hale Agilent Technologies, Santa Clara, CA Introduction Experimental Adeno-associated viral vectors (AAVs) are promising delivery vehicles for the next…

[ APPLICATION NOTE ] Anion-Exchange Chromatography for Determining Empty and Full Capsid Contents in Adeno-Associated Virus Hua Yang, Stephan Koza, and Weibin Chen Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■ ■ Empty and full AAV capsid separation Recombinant adeno-associated…

Comprehensive analysis of adeno-associated virus quality using 3 µm monodisperse Strong Anion Exchange and Size Exclusion chromatography columns Christof Mitterer1, Ke Ma2, Steven Milian3, Shane Bechler2 and Shanhua Lin2 1Thermo Fisher Scientific, Am Parir 20, 52379 Langerwehe, Germany - 2Thermo…

Application note | 001816 Biopharma Salt gradient separation and analysis of adeno-associated virus samples using a 3 μm monodisperse strong anion exchange chromatography column Authors Application benefits Ke Ma, Shane Bechler • High-resolution separation of empty and full AAV capsids…