Analytical Considerations for Extractables Screening With Liquid Chromatography-High Resolution Mass Spectrometry

Using a vacuum jacketed column with a multi reflecting time-of-flight MS to increase extractables analysis throughput whilst maintaining identification confidence Rachel Sanig1, Lee A. Gethings1, Jayne Kirk1, Richard Lock1, Bindesh Shrestha2 Waters Corporation, UK1, Waters Corporation, US2 • INTRODUCTION METHODS…

Application Note Extractables Analysis of Nasal Spray Devices Using Gas Chromatography and HighResolution Mass Spectrometry With Soft Ionization Rachel Sanig, Sarah Dowd, Jayne Kirk Waters Corporation Abstract Due to concern about the safety of components from plastic, it is crucial…

Poster Reprint ASMS 2025 Poster number TP 323 Getting the most out of your Extractables and Leachables LC/MS Analysis with the Proposed US FDA CDRH CLAP Standard Set Sierra D. Durham and David A. Weil Agilent Technologies, Santa Clara, CA…

EXTRACTABLES ANALYSIS OF NASAL SPRAY DEVICES USING GAS CHROMATOGRAPHY AND QUADRUPOLE TIME OF FLIGHT HIGH-RESOLUTION MASS SPECTROMETRY WITH SOFT IONIZATION Rachel Sanig, Hania Khoury-Hollins, Jayne Kirk, Lee Gethings, Richard Lock Waters Corporation, Altrincham Road, Wilmslow, Cheshire, SK9 4AX, UK INTRODUCTION…