Capillary Chromatography for Therapeutic Proteins and Their Subunit Analysis Using MAbPac RP Column

Application Note Biopharma/Pharma Rituximab Biosimilar Analysis Using the Agilent InfinityLab Pro iQ Plus LC/MS Author Abstract Ravindra Gudihal Agilent Technologies, Inc. The biotherapeutics field is rapidly expanding, with recombinant monoclonal antibodies (mAbs) emerging as key products, particularly in the development…

Application Note Pharma & Biopharma A Comparative Study of the Intact Mass, Subunit Mass, and Released Glycans of Two Rituximab Biosimilars Using High-Resolution LC/MS Author Brian Liau Agilent Technologies, Inc. Introduction Recent years have witnessed a rapid increase in the…

Agilent-NISTmAb Intact & Subunit Analysis Using Reversed Phase Agilent BioHPLC Columns Application Compendium Contents Agilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted from NISTmAb RM 8671 batch. Quality control (QC) testing is performed using Agilent LC-MS system. QC batch release test…

RES MS analysis of antibodies at the protein and peptide levels is critical during development and production of biopharmaceuticals. The compositions of current generation therapeutic proteins are often complex due to their heterogeneity caused by various modifications which are relevant…