A Sensitive Method for Direct Analysis of Impurities in Apramycin and Other Aminoglycoside Antibiotics Using Charged Aerosol Detection

Charged Aerosol Detection 101 Dr. Alexander Schwahn European Sales Support Expert for Biopharma Industry Thermo Fisher Scientific, Reinach, Switzerland The world leader in serving science Outline • • • • • • 2 Introduction to charged aerosol detection (CAD) How…

Bruce Bailey, Ph. D. Thermo Fisher Scientific, Chelmsford, MA, USA Ap plica t ion Note 1 1 26 Metoprolol and Select Impurities Analysis Using a Hydrophilic Interaction Chromatography Method with Combined UV and Charged Aerosol Detection Key Words Vanquish UHPLC…

Table of contents Summary Overview Excipient function Measurement Charged Aerosol Detector Universal detection Uniform response Working principles (U)HPLC Systems with CAD Columns choice Excipients overview Adjuvants Amino acids Carbohydrates Counterions Nonionic surfactants Polyethylene glycol Proteins and excipients HPLC-Charged Aerosol Detection…

Case study | 001444 Pharma Quantifying more with less: Implementing charged aerosol detection to improve drug safety University of Wuerzburg “With Thermo Fisher Scientific at our side, we always have the opportunity to investigate fundamental questions such as the meaning…