Quantification of paclitaxel, its degradants, and related substances using UHPLC with charged aerosol detection

TECHNICAL NOTE 72806 Charged aerosol detection - factors affecting uniform analyte response Authors Michael Menz1, Benjamin Eggart1, Katherine Lovejoy1, Ian Acworth2, Paul Gamache2, Frank Steiner1 Thermo Fisher Scientific, Germering, Germany 1 ²Thermo Fisher Scientific, Chelmsford, MA, USA Table of Contents…

TECHNICAL NOTE 73449 Why use charged aerosol detection with inverse gradient? Authors: Sylvia Grosse1, Tibor Muellner1, Katherine Lovejoy1, Ian Acworth2, Paul Gamache2 Thermo Fisher Scientific, Germering, Germany 2 Thermo Fisher Scientific, Chelmsford, MA, USA 1 Keywords: Vanquish Duo for Inverse…

Productivity enhancement with liquid chromatography solutions Application compendium Introduction Table of contents Pharma/BioPharma • Peptide mapping analyses • Acetaminophen impurities • Quantification of paclitaxel • Aggregate analysis of monoclonal antibodies • Simultaneous analysis of monoclonal antibodies • Doubling throughput •…

Discover what you’re missing Thermo Scientific Charged Aerosol Detectors Hidden peaks revealed The analyte detection challenge No single liquid chromatography (LC) detector delivers ideal results. Often, one analyte responds more strongly than another, or may not respond at all. What…