Charged aerosol detection - factors affecting uniform analyte response

APPLICATION NOTE 72944 Quantitation of tenofovir and impurities in multi-component drug products by ternary gradient reversed-phase chromatography with charged aerosol detection Author Katherine Lovejoy Thermo Fisher Scientific, Germering, Germany Application benefits • Improves single-calibrant quantitation of charged analytes by taking…

APPLICATION NOTE 72944 Quantitation of tenofovir and impurities in multi-component drug products by ternary gradient reversed-phase chromatography with charged aerosol detection Author Katherine Lovejoy Thermo Fisher Scientific, Germering, Germany Application benefits • Improves single-calibrant quantitation of charged analytes by taking…

Discover what you’re missing Thermo Scientific Charged Aerosol Detectors Hidden peaks revealed The analyte detection challenge No single liquid chromatography (LC) detector delivers ideal results. Often, one analyte responds more strongly than another, or may not respond at all. What…

Charged Aerosol Detection: Factors Affecting Uniform Analyte Response Katherine Lovejoy, Michael Menz, Benjamin Eggart, Frank Steiner, Ian Acworth and Paul Gamache, Thermo Fisher Scientific, Dornierstrasse 4, 82110 Germering, Germany CAD UNIFORM RESPONSE ABSTRACT The charged aerosol detector (CAD) uses evaporative…