Adeno-associated virus capsid protein characterization and host cell protein profiling using micro-flow UHPLC-Orbitrap MS

Adeno-Associated Virus Host Cell Protein Profiling Using Micro-flow Separation on a UHPLC-HRAM MS Platform Reiko Kiyonami1, Jennifer Sutton1, Kelly Murphy1, Katy Irvin2, Min Du3, 1Thermo Fisher Scientific, San Jose, CA; 2Thermo Fisher Scientific, Frederick, MD; 3Thermo Fisher Scientific, Cambridge, MA…

Application Note Biopharma/Pharma Adeno-Associated Virus Characterization with Agilent 6545XT AdvanceBio LC/Q-TOF and Protein Metrics Byos Software Authors Wendi A. Hale and Christopher M. Colangelo Agilent Technologies Inc. Lexington, MA, USA Michelle English Protein Metrics Cupertino, CA, USA Abstract This application…

APPLICATION NOTE 74109 Comprehensive identification and label-free quantitation of host cell protein contaminants using BioPharma Finder 4.1 software Authors: Silvia Millán-Martín,1 Sara Carillo,1 Jonathan Bones1, Jennifer Sutton2 National Institute for Bioprocessing Research and Training (NIBRT), Dublin, Ireland 1 2 Thermo…

APPLICATION NOTE 74162 LC-MS-based host cell protein (HCP) identification and monitoring during biopharmaceutical downstream process development Authors: Xiaoxi Zhang1, Zijuan Chen2, Bingnan Li2, Jennifer Sutton3, Min Du4 Thermo Fisher Scientific 1 Shanghai, China; 2 Bioprocess Design Center, Shanghai, China; 3…