High throughput analysis of synthetic DNA using a compliant LC-MS based workflow

Biopharma By your side Accelerating biotherapeutic development Enabling every step of your biotherapeutic development We equip you to overcome today’s and tomorrow’s challenges with tools and expertise to advance life-changing biotherapeutics to market faster than ever before. Your molecules are…

Oligonucleotides Capillary flow ion pair reversed-phase separation for very sensitive oligonucleotide LC-HRMS analysis and characterisation Ulrik H. Mistarz1, Shanhua Lin2, Shane L. Bechler2, Brandon H. Robson2, Ken Cook3 1) Thermo Fisher Scientific, Allerød, Denmark, 2) Thermo Fisher Scientific, Sunnyvale, CA…

Customer application note | 000723 Biotechnology mRNA direct sequence mapping using automated partial digestion with magnetic nuclease and LC-HRMS Authors Application benefits Mark Dickman1, Christina Vanhinsbergh1, Jon Bardsley , Ken Cook , Andrew 2 2 Williamson2, Jennifer Sutton3, Keeley Murphy3…

Biopharmaceuticals Analytical solutions for mRNA vaccines and therapeutics Table of contents mRNA vaccines and therapeutics mRNA characterization Lipid nanoparticle characterization Critical quality attributes of mRNA therapeutics Direct mRNA sequence confirmation LNP composition analysis by LC-CAD Optimize impurity analysis with ease…