Overcoming the Challenges of Bispecific Antibody Characterization Using New Column Chemistries to Detect Product Impurities

Application Note Biopharmaceuticals Surmounting the Challenges of Bispecific Antibody Characterization Using new optimized column chemistries to detect product impurities during manufacturing or storage Authors Andrea Angelo Tripodi, David L. Wong, JianQiu Mi, and Veronica Qin Agilent Tecnologies, Inc. Abstract Bispecific…

Agilent BioHPLC Columns Characterization of NIST Monoclonal Antibody Critical Quality Attributes Application Compendium Contents Agilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted from NISTmAb RM 8671 batch. Quality control (QC) testing is performed using Agilent LC-MS system. QC batch release test…

Biopharma Compendium Accelerate Your CQA Efficiency and Approach it with Multi-Attribute Methodology Breakthroughs to Increase the Efficiency of Critical Quality Attribute (CQA) Testing and Allow for a Multi- Attribute Method (MAM) Production of therapeutic monoclonal antibodies (mAbs) relies on living…

Agilent-NISTmAb Intact & Subunit Analysis Using Reversed Phase Agilent BioHPLC Columns Application Compendium Contents Agilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted from NISTmAb RM 8671 batch. Quality control (QC) testing is performed using Agilent LC-MS system. QC batch release test…