PASEF for sensitive shotgun proteomics: toward single cell analysis

Accurate Label-Free Protein Quantitation on the timsTOF Pro with 4D-Proteomics™ The timsTOF Pro platform brings together two unique technologies, namely Trapped Ion Mobility Spectrometry (TIMS) mode operation at the front-end and Parallel Accumulation Serial Fragmentation (PASEF [1]) for data acquisition.…

timsTOF Pro with PASEF and Evosep One: Maximizing throughput, robustness and analytical depth for shotgun proteomics The timsTOF Pro powered by PASEF enables sequencing speed of > 120 Hz, high sensitivity and robustness as well as an additional dimension of…

PASEF™ on a timsTOF Pro defines new performance standards for shotgun proteomics with dramatic improvements in MS/MS data acquisition rates and sensitivity Trapped ion mobility spectrometry coupled with quadrupole time-of-flight mass spectrometry (timsTOF Pro) offers a unique dimension of characterization…

Short gradients with Bruker’s nanoElute coupled to the timsTOF Pro with PASEF —Throughput and deep proteome measurements The nanoElute optimized for high throughput in chromatographic separation together with the timsTOF Pro powered by PASEF and the additional dimension of separation…