High-throughput Analysis of DNA-Modifying Enzymes by an Agilent RapidFire System

High-Throughput Analysis of Epigenetic Targets with Agilent RapidFire/MS Systems: Sirtuin (SIRT) Enzymes Application Note Author Introduction Peter Rye, Lauren Frick, and William LaMarr Agilent Technologies, Inc. Wakefield, MA USA Histones and other proteins are subject to a variety of posttranslational…

High-Throughput MS Detection of Histone H3 Demethylation by Lysine-Specific Demethylase 1 (LSD1) Application Note Author Introduction Peter Rye, Lauren Frick, and William LaMarr Agilent Technologies, Inc. Wakefield, MA USA The field of epigenetics focuses on the investigation of enzymes that…

RapidFire for Automated High-Throughput LC/MS Proven. Rapid. Complete. Application Compendium Table of Contents Introduction3 Application Notes Method Development High-Throughput (Sub-2.5 Second) Direct Injection Analysis by  Mass Spectrometry 4 Automated Method Development Using the Agilent RapidFire  High-Throughput Mass Spectrometry…

Application Note Drug Discovery A study of SIRT1- and SIRT2‑Mediated Deacetylation Using the Agilent RapidFire high-throughput mass spectrometry system Authors Abstract Peter Rye, Lauren Frick, and William Lamarr Agilent Technologies, Inc. The Agilent RapidFire high-throughput mass spectrometry (MS) system is…