High-Throughput Analysis of Epigenetic Targets with Agilent RapidFire/MS Systems: Sirtuin (SIRT) Enzymes

High-Throughput MS Detection of Histone H3 Demethylation by Lysine-Specific Demethylase 1 (LSD1) Application Note Author Introduction Peter Rye, Lauren Frick, and William LaMarr Agilent Technologies, Inc. Wakefield, MA USA The field of epigenetics focuses on the investigation of enzymes that…

Application Note Drug Discovery A study of SIRT1- and SIRT2‑Mediated Deacetylation Using the Agilent RapidFire high-throughput mass spectrometry system Authors Abstract Peter Rye, Lauren Frick, and William Lamarr Agilent Technologies, Inc. The Agilent RapidFire high-throughput mass spectrometry (MS) system is…

High-Throughput Lead Discovery with Agilent RapidFire/MS Systems: Analysis of UDP-3-O-(R-3-hydroxymyristoyl)-NAcetylglucosamine Deacetylase (LpxC) Application Note Authors Introduction William Lamarr, Lauren Frick, and Peter Rye Agilent Technologies, Inc. Wakefield, MA USA The RapidFire High-throughput Mass Spectrometry System provides drug discovery researchers with…

High-Throughput Lead Discovery with Agilent RapidFire/MS Systems: Analysis of Acetyl-Coenzyme A Carboxylase (ACC) Application Note Authors Introduction William Lamarr, Lauren Frick, and Peter Rye Agilent Technologies, Inc. Wakefield, MA USA The RapidFire High-throughput Mass Spectrometry System provides drug discovery researchers…