ACCURATE MASS DETERMINATION OF NARROW ELECTROPHORETIC PEAKS USING AN ORTHOGONAL ACCELERATION TIME-OF-FLIGHT MASS SPECTROMETER

Monoclonal Antibody Charge Heterogeneity Analysis by CZE and CZE/MS Comparison of charge variant profiles of Rituximab Innovator and Biosimilar mAbs Application Note Biopharmaceutical Author Introduction Suresh Babu C.V. During biosysnthesis, various post-translational modifications (PTMs) will lead to charge heterogeneity in…

ApplicationNOTE THE USE OF Q-Tof™ FOR THE CHARACTERIZATION OF AN N-LINKED GLYCOSYLATION SITE IN NATIVE CAULIFLOWER XYLOGLUCAN ENDOTRANS GLYCOSYLASE Iain Campuzano1, James Langridge1, Harry Brumer2, Hongbin Henriksson2 and Tuula Teeri2 Waters Corporation, Manchester, UK 2Dept. of Biotechnology, Royal Institute of…

Application Note Pharma & Biopharma Monoclonal Antibody Charge Variants Identification by Fully Automated Capillary Isoelectric Focusing – Mass Spectrometry Authors Tony Wang, James Xia, and Rena Wang CMP Scientific Corp, Brooklyn, NY, USA Jens Meixner Agilent Technologies, Inc. Waldbronn, Germany…

Transformative Workflows for Protein Characterization: ECD and Multidimensional Separations Expert Insights Sponsored by Expert Insights Contents Introduction 3 The Role of Electron Capture Dissociation in Biomolecular Analysis Adapted from Cooper, et al. 4 Offline Coupling of Hydrophobic Interaction Chromatography– Capillary…