Utilizing Enantiomeric Separations in Bioanalysis

Impact of Reversed-Phase Chiral Chromatography on the LC-MS Analysis of Drugs in Biological Fluids •David S. Bell, Carmen T. Santasania, Jennifer Claus, Wayne K. Way, and Craig R. Aurand Supelco, Div. of Sigma-Aldrich, Bellefonte, PA 16823 USA sigma-aldrich.com T411043 Abstract…

Basics of Chiral HPLC Definitions Principles Available CSPs Mobile phase types T408109 sigma-aldrich.com The Field of Stereochemistry 1. All isomers have same chemical formula but differ in the arrangement of certain chemical groups in space. 2. Many types of isomers…

HPLC Enantiomeric Separations of Pharmaceuticals Using Polar Organic Mobile Phases •J.T. Lee and William Campbell Supelco, Div. of Sigma-Aldrich, Bellefonte, PA 16823 USA sigma-aldrich.com T411054 Agenda • • • • • • • • • Background Benefits Mechanisms Separation Comparisons…

LC-MS Resource Guide A Comprehensive Portfolio for Consistent Results in Routine and Advanced LC-MS applications The life science business of Merck KGaA, Darmstadt, Germany operates as MilliporeSigma in the U.S. and Canada. LC-MS Resource Guide Maximize the Performance of Your…