Retention Time, Product Ion, and CCS Characterization of the Constituents of a FDA-Approved Small Molecule Pharmaceuticals Library

Application Note High Throughput Non-Targeted Screening Using a Rapid Gradient Microbore UPLC Method and a Library of FDA-Approved Small Molecule Drugs Michael McCullagh, Jeff Goshawk, Russell J. Mortishire-Smith Waters Corporation Abstract Rapid gradient microbore UltraPerformance Liquid Chromatography was combined with…

A COMPARISON OF CONVENTIONAL AND RAPID GRADIENT MICROBORE LC CYCLIC™ ION MOBILITY MASS SPECTROMETRY FOR NON-TARGETED SCREENING OF BIOLOGICAL MATRICES 1 Michael McCullagh, 1Martin Palmer, 1Russell Mortishire-Smith, 1Emma Marsden-Edwards, 1Dale Cooper-Shepherd, 2Robert Plumb, 2Iggy Kass and 1Jeff Goshawk 1 Waters…

Application Note Extractables, Leachables, and Contact Materials: The Invaluable Benefit of Ion Mobility-Enhanced Mass Spectrometry Libraries Michael McCullagh, Russell J. Mortishire-Smith, Jeff Goshawk, Jane Cooper, Markus Obkircher, Hanspeter Sprecher, Rudolf Koehling, Matthias Nold, Jens Jacobsen, Rachel Sanig Waters Corporation, Merck…

[ APPLICATION NOTE ] Use of Ion Mobility TWCCSN2 Values in Non-targeted Food Additives Screening Michael McCullagh,1 Jeff Goshawk, 1 and Severine Goscinny2 1 Waters Corporation, Wilmslow, UK; 2 Sciensano, Brussels, Belgium APPLICATION BENEFITS ■ ■ ■ ■ ■ INTRODUCTION…