Future Proofing the Biopharmaceutical QC Lab:Benefits of Automating Mobile Phase Delivery to Improve pH Consistency in Size Exclusion Chromatography Methods

MAIN MENU TABLE OF CONTENTS [ APPLICATIONS NOTEBOOK ] BIOSEPARATIONS Tools, Techniques, and Insights into Biopharmaceutical Analysis INT RODUCTION Biopharmaceuticals have emerged as a dominant class due to their specificity and efficacy. T he production of biopharmaceuticals, however, is distinctly…

[ APPLICATION NOTEBOOK ] SIZE-EXCLUSION CHROMATOGRAPHY (SEC) OF PEPTIDES, PROTEINS, AND AAVs [ SIZE-EXCLUSION CHROMATOGRAPHY ] [ SIZE-EXCLUSION CHROMATOGRAPHY ] Introduction Gel-permeation chromatography (GPC), size-exclusion chromatography (SEC), and gel-filtration chromatography (GFC) are commonly used terms to describe a liquid chromatographic…

Future-proofing the Biopharmaceutical QC Laboratory: Using the ACQUITY UPLC H-Class Bio System to Run SEC-HPLC and SEC-UPLC Eoin F.J. Cosgrave and Sean M. McCarthy Waters Corporation, Milford, MA, USA A P P L I C AT I O N B…

Future-proofing the Biopharmaceutical QC Laboratory: Integrating Auto • Blend Technology to Improve Routine Peptide Mapping Eoin F.J. Cosgrave and Sean M. McCarthy Waters Corporation, Milford, MA, USA A P P L I C AT I O N B E N…