1Rapid, Reliable Metabolite Ratio Evaluation for MIST Assessments in Drug Discovery and Preclinical Studies

Improving the Cleanliness of DBS Extracts using the Ostro Pass-through 96-well Sample Preparation Plate and Single Step Method Jessalynn P. Wheaton, Erin E. Chambers, and Kenneth J. Fountain A P P LIC AT ION BEN EFIT S n INT RODUC…

HybridSPE™ - Precipitation Technology Bridging the Gap between Simplicity & Selectivity in Sample Prep Updated: Mar 13 ‘09 T408104 sigma-aldrich.com Agenda • Introduction • HybridSPE-PPT (How does it work?) • LC Column Phospholipid Accumulation • Comparative Studies • Phospholipid Removal…

[ APPLICATION NOTEBOOK ] Forensic Toxicology Application Notebook BATTLING THE PROLIFERATION OF DRUGS IS NOT EASY. IDENTIFYING THEM CAN BE. FORENSIC TOXICOLOGY PHARMACEUTICAL As new forms of “designer” drugs threaten public safety, there is an immediate need for advanced ways…

[ APPLICATION NOTE ] Bioanalytical LC-MS Quantification of Itaconic Acid: A Potential Metabolic Biomarker of Inflammation Kathryn Brennan, Mary Lame, Jonathan Danaceau, Christopher Henry, and Paul Rainville Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ ■■ ■■ ■■ INTRODUCTION…