Utilisation of Ion Mobility Enabled Collisional Cross Section Measurements for the Comparison of Metabolites across Differing Chromatographic Methods

[ APPLICATION NOTE ] Integrating Ion Mobility into Routine Drug Metabolite Identification Studies Using the Vion IMS QTof Mass Spectrometer Jayne Kirk, 1 Russell Mortishire-Smith, 1 and Mark Wrona 2 1 Waters Corporation, Wilmslow, UK 2 Waters Corporation, Milford, MA,…

Application Note Use of Predicted Versus Measured CCS Values from Different Instrument Platforms, and Isomer Separation on the SELECT SERIES Cyclic IMS David Higton, Christian Lanshoeft, Frederic Lozac'h Waters Corporation, Novartis Pharma AG Abstract Biotransformation activities require the comparison of…

[ APPLICATION NOTE ] Ion Mobility-enabled Data-dependent Experiments Distinguishing Co-eluting Isomeric Metabolites Using an IMS-QTof Mass Spectrometer Jayne Kirk, 1 Russell Mortishire –Smith, 1 Robert Beecher, 1 Richard Clayton, 2 Catherine Holsworth 2 and Mark Wrona3 1 Waters Corporation, Wilmslow,…

[ APPLICATION NOTE ] Unparalleled Multi-Factor Authentication Mass Spectrometry of Complex Natural Products Utilizing UPLC and Ion Mobility Michael McCullagh, Russell Mortishire-Smith, and Jeff Goshawk Waters Corporation, Wilmslow, UK APPLICATION BENEFITS ■ ■ Unique multi-factor authentication The application of LC-MS-based…