Top-down Monoclonal Antibody (mAb) Analysis Using CID and ETD Fragmentation and the UNIFI Scientific Information System

BIOPHARMACEUTICAL PLATFORM SOLUTION Key Applications TABLE OF CONTENTS Biopharmaceutical Platform Solution with UNIFI: Key Applications Intact Protein MS Analysis I Peptide Mapping I Released Glycan Analysis I Bioseparations Biotherapeutic proteins – such as monoclonal antibodies (mAbs), biosimilars, and antibody drug…

Poster Note 64778 Top-down Characterization of Monoclonal Antibody on an Orbitrap Fusion Lumos™ Tribrid Mass Spectrometer Seema Sharma, Stephane Houel, Christopher Mullen, Chad Weisbrod, Romain Huguet, John Syka, Dave Horn, Jonathan Josephs, Jae Schwartz, Vlad Zabrouskov Thermo Fisher Scientific, San…

DATA INDEPENDENT TOP-DOWN MASS SPECTROMETRY FACILITATED BY A NEW MSE PROCESSING TOOL Lindsay J. Morrison and Barbara J. Sullivan Waters Corporation, Beverly, USA METHODS OVERVIEW A software for processing of chromatographic top-down MSE data from the Synapt G2-Si is demonstrated…

Application Note mAb Subunit Analysis Using the SYNAPT XS High Resolution Mass Spectrometer Henry Shion, Scott J. Berger, Ying Qing Yu Waters Corporation This is an Application Brief and does not contain a detailed Experimental section. Abstract The SYNAPT XS…