Enhanced Specificity Provides Increased Quantitative Accuracy When Using SONAR for the Analysis of Low Level Lipids in Plasma-Based Extracts

[ TECHNOLOGY BRIEF ] Analysis of Plasma Proteome for a Respiratory Disease Cohort Using SONAR on a SYNAPT XS Mass Spectrometer Christopher Hughes, 1 Lee Gethings,1 Joanne Ballantyne,1 and Robert Plumb 2 1 Micromass UK Limited, Wilmslow, Cheshire, UK; 2…

[ TECHNOLOGY BRIEF ] Increased Specificity, Improved Lipidomic Clarity, and Identification Confidence with SONAR Adam King,¹ Lee A. Gethings,¹ Robert S. Plumb,¹ and Ian D. Wilson² ¹Waters Corporation; ²Imperial College London Implementing SONAR improves spectral clarity and thereby increases certainty…

COMPARISON OF FAST SCANNING DATA DEPENDENT AND DATA INDEPENDENT ACQUISITION METHODS FOR A MULTI-OMIC CANCER STUDY USING HIGH-SPEED CHROMATOGRAPHY Lee A. Gethings1, Matthew Daly1, Martin Palmer1, Richard Lock1, Jason Wildgoose1, James I. Langridge1 1 Waters Corp., Wilmslow, Cheshire, United Kingdom…

[ APPLICATION NOTE ] Rapid Qualitative Analysis and Absolute Quantification of Plasma Proteins Using SONAR with Biognosys PQ500 for Proteomic Clinical Research Studies Christopher J. Hughes, 1 Sarah Lennon,1 Lee A. Gethings,1 Florian Marty, 2 Sebastian Müller, 2 Lukas Reiter,…