MS Identification of Trace level Impurities from a Non-MS Compatible Mobile Phase Using ACQUITY UPLC System with 2D Technology by Heart-cutting and Online Sample Concentration

[ APPLICATION NOTE ] Mass Detection Coupled to a USP Method for Lidocaine and Prilocaine Cream Using Multi-dimensional Liquid Chromatography Margaret Maziarz, Claude Mallet, Paul Rainville, and Mark Wrona Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ INTRODUCTION Easy…

Routine MS Detection for USP Chromatographic Methods Daniel S. Root, Thomas E. Wheat, and Patricia McConville Waters Corporation, Milford, MA, USA A P P L I C AT I O N B E N E F I T S INT…

[ APPLICATION NOTE ] Compliant Monitoring of Monoclonal Antibody Titer and Primary Structure Attributes Using a 2D-LC/MS System with UNIFI Informatics Brooke M. Koshel, Robert E. Birdsall, and Ying Qing Yu Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■…

[ APPLICATION NOTE ] Effective Determination of Pharmaceutical Impurities by Two Dimensional Liquid Chromatography Zhimin Li, Paula Hong, and Patricia McConville Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ INTRODUCTION Increase productivity through targeted Analysis of many pharmaceutical compounds…