High Sensitivity LC-MS/MS Quantification of Monoclonal Antibody Drugs in Rat Plasma Using a Standardized Sample Preparation Workflow

[ APPLICATION NOTE ] Development of a Hybrid Immunoaffinity-LC-MS/MS Method for the Quantification of Active Biotherapeutics Targeting TNF-α in Serum Caitlin Dunning and Mary Lame Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ High analytical sensitivity Tumor Necrosis Factor…

Waters Application Notes ProteinWorks OUR SCIENTISTS Erin E. Chambers As a principal scientist, Erin has been working almost exclusively on peptide and protein bioanalysis for the last seven years, while managing small and large molecule bioanalysis and clinical research applications…

ProteinWorks TA K E T H E COM P L EX IT Y OU T O F LA RG E MO L ECU L E QUANT IFICAT ION As the therapeutic and research landscape changes from small molecule to large…

A Universal, Optimized SPE Protocol for Clean-up of Tryptic Peptides in Protein Bioanalysis Mary Lame, Hua Yang, Sherri Naughton, and Erin Chambers G OA L As of 2013, there were 338 new monoclonal antibody To demonstrate the performance of an…