Increased Resolving Power for Acidic Glycans with an MS-Compatible Anion Exchange Reversed Phase Separation

Application Note Released Glycan Analysis of Erythropoietin Using the ACQUITY Premier Glycan BEH C 18 AX Column and BioAccord System with ACQUITY Premier Ximo Zhang, Robert E. Birdsall, Ying Qing Yu Waters Corporation Abstract The abundance and structure of highly…

Application Note Characterization of Released N-linked Glycans in Biosimilar mAb Drug Products Using the Xevo™ G3 QTof Kellen DeLaney, Yamin Htet, Ying Qing Yu Waters Corporation Abstract As an increasing number of biosimilar monoclonal antibodies (mAb) are being developed, there…

MAIN MENU TABLE OF CONTENTS [ APPLICATIONS NOTEBOOK ] BIOSEPARATIONS Tools, Techniques, and Insights into Biopharmaceutical Analysis INT RODUCTION Biopharmaceuticals have emerged as a dominant class due to their specificity and efficacy. T he production of biopharmaceuticals, however, is distinctly…

Application Note Improving Released N-glycan Analysis in Biotherapeutic Development Using the ACQUITY Premier Solution with MaxPeak High Performance Surfaces (HPS) Technology Ximo Zhang, Jacob Kellett, Robert E. Birdsall, Ying Qing Yu Waters Corporation Abstract Characterization and monitoring of glycosylation are…