Noc vědy 2026 - Komunikace

Třetí den <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/cs-cz/all/events/930">27. Školy hmotnostní spektrometrie</a>, středa 23. září 2026, se dopoledne nesl ve znamení omických přístupů a metod, které posouvají možnosti běžné LC-MS analýzy. Zdeněk Spáčil otevřel program přehledem akvizičních strategií od full scanu a MS/MS přes DDA, DIA/SWATH a PRM/MRM až po HRMS, na který Jaroslava Friedecká navázala tématem společného vyhodnocování metabolomických, proteomických a lipidomických dat. Sekce „Za hranicemi rutinní MS“ pak ukázala další směry současné hmotnostní spektrometrie: Pavel Hrouzek představil využití stabilních izotopů při studiu metabolických drah, Robert Jirásko se zaměřil na iontovou mobilitu v LC/MS při analýze malých molekul a dopolední odborný blok uzavřela přednáška společnosti <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/companies/43">Shimadzu</a> věnovaná ionizační technologii <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/cs-cz/lcms/library?mainauthorItems=53&amp;search=SICRIT">SICRIT®</a>.Po intenzivním odborném programu přišlo na řadu tradiční kulturně-poznávací odpoledne. Účastníci si mohli vybrat mezi návštěvou Vyššího Brodu a tamního kláštera, výletem do Českého Krumlova spojeným s prohlídkou grafitového dolu, pěší túrou na Vítkův kámen nebo individuálním programem, jehož součástí byl také turnaj ve stolním fotbálku. Večer pak třetí konferenční den pokračoval společenským programem společnosti <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/companies/43">Shimadzu</a>, tentokrát v podobě Silent disco a tanečního večera.<h3>Program</h3><blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/program_Skola_MS_2026_final_8c8cf90056.pdf">Finální program 27. Školy MS je ke stažení zde</a></blockquote><h4>Středa, 23. 9. 2026</h4><h5>SEKCE VII. Od MS k omikám</h5><h5>08:30 – 09:15 Strategie akvizice v LC-MS: full scan vs. MS/MS, DDA vs. DIA (SWATH), PRM/MRM, HRMS&nbsp;</h5><ul><li>Zdeněk Spáčil&nbsp;</li></ul><h5>09:15 – 10:00 Kombinovaná analýza metabolomických, proteomických a lipidomických dat&nbsp;</h5><ul><li>Jaroslava Friedecká&nbsp;</li></ul><h5>10:00 – 10:30 Přestávka na kávu&nbsp;</h5><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Skola_hmotnostni_spektrometrie_27_Skola_MS_2026_den_3_prestavka_na_kavu_stanek_Waters_c38a261302.jpg" alt="Škola hmotnostní spektrometrie: 27. Škola MS 2026 - den 3: Přestávka na kávu - stánek Waters" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Skola_hmotnostni_spektrometrie_27_Skola_MS_2026_den_3_prestavka_na_kavu_stanek_Waters_c38a261302.jpg 208w," sizes="100vw" width="1600" height="1200"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Skola_hmotnostni_spektrometrie_27_Skola_MS_2026_den_3_prestavka_na_kavu_stanek_Phenomenex_41f63e651f.jpg" alt="Škola hmotnostní spektrometrie: 27. Škola MS 2026 - den 3: Přestávka na kávu - stánek Phenomenex" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Skola_hmotnostni_spektrometrie_27_Skola_MS_2026_den_3_prestavka_na_kavu_stanek_Phenomenex_41f63e651f.jpg 208w," sizes="100vw" width="1600" height="1200"><h5>SEKCE VIII. Za hranicemi rutinní MS&nbsp;</h5><h5>10:30 – 11:00 Od izotopové obálky k metabolickým drahám: využití stabilních izotopů při studiu primárního metabolismu a biosyntézy specializovaných metabolitů&nbsp;</h5><ul><li>Pavel Hrouzek&nbsp;</li></ul><h5>11:00 – 11:30 Současné techniky iontové mobility v LC/MS a jejich využití při analýze malých molekul&nbsp;</h5><ul><li>Robert Jirásko&nbsp;</li></ul><h5>11:30 – 12:00 <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/companies/43">Shimadzu</a>: SICRIT®: Nová dimenze v MS ionizaci&nbsp;</h5><ul><li>Jan Buček</li></ul><h5>12:00 – 13:30 Oběd&nbsp;</h5><h5>KULTURNĚ POZNÁVACÍ ODPOLEDNE&nbsp;</h5><ul><li>A Vyšší Brod – procházka městem, prohlídka kláštera&nbsp;</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Skola_hmotnostni_spektrometrie_27_Skola_MS_2026_den_3_navsteva_klastera_b29f09e792.jpg" alt="Škola hmotnostní spektrometrie: 27. Škola MS 2026 - den 3: Vyšší Brod – procházka městem, prohlídka kláštera " srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Skola_hmotnostni_spektrometrie_27_Skola_MS_2026_den_3_navsteva_klastera_b29f09e792.jpg 233w," sizes="100vw" width="1600" height="1072"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Skola_hmotnostni_spektrometrie_27_Skola_MS_2026_den_3_navsteva_klastera_2_a5d6ebf850.jpg" alt="Škola hmotnostní spektrometrie: 27. Škola MS 2026 - den 3: Vyšší Brod – procházka městem, prohlídka kláštera " srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Skola_hmotnostni_spektrometrie_27_Skola_MS_2026_den_3_navsteva_klastera_2_a5d6ebf850.jpg 208w," sizes="100vw" width="1600" height="1201"><ul><li>B Český Krumlov – prohlídka města, grafitový důl&nbsp;</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Skola_hmotnostni_spektrometrie_27_Skola_MS_2026_den_3_navsteva_grafitoveho_dolu_8eb08e949b.jpg" alt="Škola hmotnostní spektrometrie: 27. Škola MS 2026 - den 3: Návštěva grafitového dolu" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Skola_hmotnostni_spektrometrie_27_Skola_MS_2026_den_3_navsteva_grafitoveho_dolu_8eb08e949b.jpg 207w," sizes="100vw" width="1600" height="1210"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Skola_hmotnostni_spektrometrie_27_Skola_MS_2026_den_3_prohlidka_mesta_2_0d7ca18616.jpg" alt="Škola hmotnostní spektrometrie: 27. Škola MS 2026 - den 3: Prohlídka města" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Skola_hmotnostni_spektrometrie_27_Skola_MS_2026_den_3_prohlidka_mesta_2_0d7ca18616.jpg 208w," sizes="100vw" width="1600" height="1200"><ul><li>C Vítkův kámen – pěší túra&nbsp;</li><li>D Individuální program&nbsp;</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Skola_hmotnostni_spektrometrie_27_Skola_MS_2026_den_3_turnaj_ve_stolnim_fotbalku_ff528cbf26.jpg" alt="Škola hmotnostní spektrometrie: 27. Škola MS 2026 - den 3: Turnaj ve stolním fotbálku" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Skola_hmotnostni_spektrometrie_27_Skola_MS_2026_den_3_turnaj_ve_stolnim_fotbalku_ff528cbf26.jpg 208w," sizes="100vw" width="1600" height="1200"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Skola_hmotnostni_spektrometrie_27_Skola_MS_2026_den_3_turnaj_ve_stolnim_fotbalku_2_6a7eed62ef.jpg" alt="Škola hmotnostní spektrometrie: 27. Škola MS 2026 - den 3: Turnaj ve stolním fotbálku" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Skola_hmotnostni_spektrometrie_27_Skola_MS_2026_den_3_turnaj_ve_stolnim_fotbalku_2_6a7eed62ef.jpg 208w," sizes="100vw" width="1600" height="1200"><h5>19:00 – 20:30 Večeře&nbsp;</h5><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Skola_hmotnostni_spektrometrie_27_Skola_MS_2026_den_3_spolecensky_vecer_fffd0d6d88.jpg" alt="Škola hmotnostní spektrometrie: 27. Škola MS 2026 - den 3: Večerní program" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Skola_hmotnostni_spektrometrie_27_Skola_MS_2026_den_3_spolecensky_vecer_fffd0d6d88.jpg 208w," sizes="100vw" width="1600" height="1200"><h5>20:30 – ??? Společenský večer firmy <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/companies/43">Shimadzu</a> - Silent disco</h5><ul><li>Taneční večer</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Skola_hmotnostni_spektrometrie_27_Skola_MS_2026_den_3_silent_disco_7732142c92.jpg" alt="Škola hmotnostní spektrometrie: 27. Škola MS 2026 - den 3: Společenský večer firmy Shimadzu - Silent disco" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Skola_hmotnostni_spektrometrie_27_Skola_MS_2026_den_3_silent_disco_7732142c92.jpg 245w," sizes="100vw" width="1600" height="900">

27. Škola MS 2026 - den 3

Nový grafenový inkoust pro výrobu levných a citlivých tištěných senzorů vyvinuli výzkumníci z CATRIN Univerzity Palackého ve spolupráci s kolegy z VŠB-Technické univerzity Ostrava a Univerzity Karlovy. Při přípravě inkoustu poprvé využili metodu atomárního inženýrství a díky navázaným atomům mědi jsou schopni detekovat velmi citlivě dopamin – neurotransmiter, který umožňuje přenos signálů mezi nervovými buňkami. Přístup <a target="_blank" rel="noopener noreferrer" href="https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.76796">představený v časopise Advanced Science</a> má velké šance uplatnit se v lékařské diagnostice.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CATRIN_Atom_po_atomu_Vedci_ukazali_novy_smer_v_lekarske_diagnostice_8a02ad6a66.webp" alt="CATRIN: Atom po atomu. Vědci ukázali nový směr v lékařské diagnostice" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CATRIN_Atom_po_atomu_Vedci_ukazali_novy_smer_v_lekarske_diagnostice_8a02ad6a66.webp 117w," sizes="100vw" width="1920" height="2560">Atomární inženýrství (single-atom engineering) umožňuje řídit chemickou reaktivitu materiálů na úrovni jednotlivých atomů. Jeho širšímu uplatnění v lékařské diagnostice však dosud bránil nedostatek atomárně upravených materiálů i absence na nich založených tisknutelných inkoustů.&nbsp;Nyní se vědcům podařilo vyvinout novou třídu atomárně dopovaných grafenových materiálů a také inkoust pro přípravu citlivých tištěných senzorů. Sázka na měď se vyplatila při detekci dopaminu, jehož sledování je důležité pro biomedicínský výzkum a vývoj pokročilých diagnostických technologií některých onemocnění včetně Alzheimerovy choroby.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CATRIN_Atom_po_atomu_Vedci_ukazali_novy_smer_v_lekarske_diagnostice_2_97e419f039.webp" alt="CATRIN: Atom po atomu. Vědci ukázali nový směr v lékařské diagnostice" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CATRIN_Atom_po_atomu_Vedci_ukazali_novy_smer_v_lekarske_diagnostice_2_97e419f039.webp 117w," sizes="100vw" width="1920" height="2560">„Vyvinutý NGA-Cu inkoust umožňuje výrobu plně inkoustově tištěných udržitelných papírových elektrod s velmi nízkými náklady. Samotný senzor vyžaduje pouze 1,3 mikrogramu aktivního inkoustu, stojí přibližně jednu korunu a dával stabilní odezvu minimálně po dobu tří měsíců. Inkoust je navíc plně kompatibilní s běžně dostupnými inkoustovými materiálovými tiskárnami. To vytváří velký potenciál pro přípravu cenově dostupných, digitálně navržených senzorů, jejichž funkci lze přizpůsobovat atom po atomu,“ uvedl korespondující autor článku Michal Otyepka.Základem pro novou generaci atomárních inkoustů byla dusíkem dopovaná grafenová kyselina (NGA), kterou vědci z CATRIN vyvinuli před několika lety. Nyní ji postupně obohacovali různými jednotlivými atomy kovů včetně mědi, železa nebo manganu.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CATRIN_Atom_po_atomu_Vedci_ukazali_novy_smer_v_lekarske_diagnostice_3_c15d831792.webp" alt="CATRIN: Atom po atomu. Vědci ukázali nový směr v lékařské diagnostice" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CATRIN_Atom_po_atomu_Vedci_ukazali_novy_smer_v_lekarske_diagnostice_3_c15d831792.webp 117w," sizes="100vw" width="1920" height="2560">„Ukázalo se, že elektrochemická odezva zásadně závisí na typu použitého atomu. Zatímco atomy mědi výrazně zesilují signál dopaminu, ostatní kovy jej naopak potlačují. Rozhodující&nbsp;tedy není jen samotná přítomnost izolovaných atomů kovu, ale také to, o jaký konkrétní kov se jedná. To je velmi důležitý poznatek pro další vývoj biosenzorů,“ objasnil první autor Martin-Alex Nalepa.Publikované výsledky představují novou třídu senzorických materiálů s velkým potenciálem v lékařské diagnostice. Vědci nabízí obecně využitelnou platformu pro vývoj grafenových inkoustů s jednotlivými atomy kovů a otevírají cestu ke škálovatelné, reprodukovatelné a materiálově úsporné výrobě pokročilých elektrochemických senzorů. „Jsme na začátku a fascinují nás nové možnosti, které se před námi otevírají. Vidíme, že změnou typu atomů můžeme řídit citlivost a selektivitu senzoru. Kromě dopaminu tak umíme velmi přesně stanovit například imunoglobuliny – protilátky, jejichž množství a typ mohou být důležitým ukazatelem autoimunitních nebo infekčních onemocnění,“ zdůraznil další z autorů článku Radek Zbořil.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CATRIN_Atom_po_atomu_Vedci_ukazali_novy_smer_v_lekarske_diagnostice_4_273cd760a5.webp" alt="CATRIN: Atom po atomu. Vědci ukázali nový směr v lékařské diagnostice" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CATRIN_Atom_po_atomu_Vedci_ukazali_novy_smer_v_lekarske_diagnostice_4_273cd760a5.webp 117w," sizes="100vw" width="1920" height="2560">Elektrochemické biosenzory mohou nalézt uplatnění nejen v medicíně, ale také při kontrole kvality potravin, monitorování pitné vody nebo sledování znečištění životního prostředí. Jejich klíčovou součástí jsou funkcionalizované elektrody, pro jejichž výrobu se ukázaly jako velmi vhodné materiály právě na bázi grafenu. Základem úspěchu olomouckých vědců byla cílená příprava grafenového inkoustu s potřebnými vlastnostmi.Výzkum podpořil projekt TECHSCALE z operačního programu Jan Amos Komenský.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CATRIN_Atom_po_atomu_Vedci_ukazali_novy_smer_v_lekarske_diagnostice_5_b1778f77f2.jpg" alt="CATRIN: Atom po atomu. Vědci ukázali nový směr v lékařské diagnostice: Projekt TECHSCALE (No.&nbsp;CZ.02.01.01/00/22_008/0004587) je financován z&nbsp;programu MŠMT&nbsp;OP&nbsp;JAK Špičkový výzkum, podpořeného z&nbsp;EFRR/ESF." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CATRIN_Atom_po_atomu_Vedci_ukazali_novy_smer_v_lekarske_diagnostice_5_b1778f77f2.jpg 245w," sizes="100vw" width="620" height="87"><blockquote><h4>Článek</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.76796">Single-Atom-Enhanced Fully Inkjet-Printed Electrochemical Sensor for Dopamine Detection</a></h4>Martin-Alex Nalepa, David Panáček, Vítězslav Hrubý, Matěj Jendřišák, Rostislav Langer, Michal Langer, Petr Jakubec, Ivan Dědek, Vojtěch Kupka, Michal Mazur, Radek Zbořil, Michal OtyepkaAdv. Sci., 2026, e76796<a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1002/advs.76796">https://doi.org/10.1002/advs.76796</a><h6>licencováno pod <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote>

Atom po atomu. Vědci ukázali nový směr v lékařské diagnostice

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Věda a výzkum

Video

Článek

Nejbližší akce

Škola hmotnostní spektrometrie je odborná vzdělávací akce pořádaná od roku 1986, která vedle zajímavých přednášek a kurzů nabízí i nespočet příležitostí k přátelským setkáním a diskusím.

Škola hmotnostní spektrometrie

Český institut výzkumu a pokročilých technologií (Czech Advanced Technology and Research Institute – CATRIN) je vysokoškolský ústav Univerzity Palackého v Olomouci. Vznikl integrací vědeckých týmů Centra regionu Haná pro biotechnologický a zemědělský výzkum (CRH), Regionálního centra pokročilých technologií a materiálů (RCPTM) a Ústavu molekulární a translační medicíny (ÚMTM) s cílem úzce propojit vědecké kapacity v oblasti biomedicíny, nanotechnologií, nových materiálů, výzkumu rostlin či biotechnologií a ještě úspěšněji čelit  globálním výzvám současného světa, k nimž patří například dopady klimatických změn, boj s novými typy patogenů, diagnostika a léčba civilizačních onemocnění, odvrácení hrozící potravinové krize, získávání a ukládání „zelené“ energie, zajištění dostatku pitné vody, ochrana životního prostředí a řada dalších.

CATRIN

Noc vědců, akce oživující v jeden večer stovky vědeckých budov, do kterých se běžný smrtelník nedostane. Návštěvníci proplouvají laboratořemi, přednáškovými místnostmi, vybuchujícími experimenty a jdou do hloubky aktuálních témat. 

Noc vědců

Agilent Technologies

Phenomenex

Thermo Fisher Scientific

Shimadzu Corporation

Waters Corporation

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</blockquote>
<blockquote>
Jo has a degree in Chemistry from the University of York and a PhD in analytical chemistry from the University of Reading. Following a post-doc in mass spectrometry in the Chemistry department at Oxford, and working as an application scientist at Waters, she has worked in and ran Proteomics Core Facilities in the UK and Germany, including the EMBL in Heidelberg, the Leibniz Institute on Aging in Jena, The Francis Crick Institute in London and CRUK Cambridge.
</blockquote>
<blockquote>
After many years as an experienced Thermo customer, Jo joined the company earlier this year as a Technical Sales Specialist, supporting the whole of the UK/Ireland, Benelux and Nordic regions, in all things proteomics.
</blockquote>
<blockquote>
When she&#39;s not talking about proteomics and mass spectrometry, Jo enjoys ceroc dancing, tennis, scuba diving, travelling, and spending time with her cats, who like to join in on Teams meetings whenever she works from home.
</blockquote>
<blockquote>
Presenter: Dr. Paul Humphrey (EMEA Senior Regional Marketing Manager, LSMS, Omics and ClinTox, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Paul has a degree in Analytical Chemistry and a PhD in Secondary Ion Mass Spectrometry from the University of Manchester.
</blockquote>
<blockquote>
He previously managed a contract analysis laboratory for several years before moving into a career in the scientific instrument manufacturing industry.
</blockquote>
<blockquote>
Initially an application chemist and product manager he moved into international scientific marketing when he joined Thermo Fisher Scientific in 1997. Since then he has worked in a variety of roles within factory, field marketing and sales office organisations. He has travelled and presented extensively and has been responsible for business in EMEA, North America and Asia/Pacific regions.
</blockquote>
<blockquote>
He lives in the UK and when not working he enjoys travelling, photography, cookery and scuba-diving.
</blockquote>
<blockquote>
Presenter: Robert van Ling (Product Manager, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Robert started his low flow chromatography career as an intern from the Technical School in Amsterdam, The Netherlands, at LC Packings in the mid-90s.
</blockquote>
<blockquote>
Since those early years, Robert has been part of the teams introducing and supporting a wide range of our nano- and capLC products, such as the UltiMate and UltiMate 3000 nanoLC systems, PepMap and EASY-Spray columns. In recent years, he has introduced our new µPAC Neo HPLC column line, an innovative and unique approach to significantly improve the performance and reliability in low flow proteomic separations.
</blockquote>
<blockquote>
Robert still lives in the wider Amsterdam region, and when not talking low flow separations very much enjoys reading fantasy, jigsaw puzzling and listening to prog and hard rock.
 
</blockquote>

Thermo Scientific: Proteomics unleashed: exclusive insights and updates from BSPR-EuPA

Proteomics unleashed: exclusive insights and updates from BSPR-EuPA

Review of presentations from the recent BSPR-EuPA conference showcasing the latest innovations.

Exclusive insights and updates from BSPR-EuPA

Per- and polyfluoroalkyl substances (PFAS) are synthetic compounds that have been the focus of research development for targeted quantitation.
PFAS are present in a variety of consumer products as well as firefighting foam that collectively can be introduced into the environment. Due to the chemical structure, these compounds are hard to break down and are therefore labeled as forever chemicals. As such, once PFAS compounds have been introduced into the environment, they can leach from their origin into the environment and have been detected in surface waters, soils, dust, plant tissue, and even in the air. Recently, concerns have escalated not only for understanding the wider environmental impact, but animal and human health have evolved as research has now focused on detecting and quantifying in human plasma and tissue.
The focus of this webinar is to explore the range of sample types examined for routine PFAS detection and quantification. Dr. John Bowden will provide an overview of the challenges non-water matrices presents for extracting and quantifying including finding blanks and validating the workflows. In addition, research will cover new methods to introduce a wide range of PFAS onto UHPLC columns and perform low-level detection and quantification of PFAS in human plasma by LC-MS/MS. The second part of the webinar will focus on targeted PFAS quantitation using the Thermo Scientific™ TSQ Quantis™ Plus mass spectrometers supporting the EPA draft method 1633 which includes sample preparation using solid phase extraction (SPE) prior to LC-MS/MS analysis. The presented workflow will demonstrate key experimental strategies to improve laboratory productivity demonstrating not only effective sample preparation options but the software solutions critical to streamline the data processing to create standard reports.
Key learning objectives: 
<ul>
<li>Evaluation of the PFAS kits on the Thermo Scientific™ Vanquish™ UHPLC systems to minimize background interference to achieve stated LOQs
</li>
<li>Review of new hardware and software components in the Thermo Scientific™ TSQ Plus mass spectrometers to boost PFAS analysis
</li>
<li>Demonstration of Thermo Scientific™ Chromeleon™ Chromatography Data System (CDS) software designed to manage the entire experiment and provide comprehensive reports to increase laboratory productivity
</li>
</ul>
Who should attend?
<ul>
<li>Laboratories that are contracted for PFAS testing
</li>
<li>Researchers looking for workflows to increase detection and quantitation limits
</li>
<li>Regulatory agencies that are focused on developing new testing methods and requirements for PFAS studies
</li>
<li>Existing Thermo Scientific™ TSQ and Thermo Scientific™ Orbitrap™ mass spectrometer operators who are interested in the next-level performance and productivity with the TSQ Plus mass spectrometer platforms
</li>
</ul>
<blockquote>
Presenter: Dr. John A. Bowden (Assistant Professor, University of Florida, (Gainesville))
</blockquote>
<blockquote>
Dr. Bowden received his B.S. in Chemistry in 2003 and in 2008 received his Ph.D. in Analytical Chemistry both from the University of Florida. John was a Postdoctoral Fellow in the Dept. of Biochemistry and Molecular Biology at St. Louis University from 2009-2011, and then a Postdoctoral Fellow with the National Institute of Standards and Technology in Charleston, S.C. from 2011-2013 and then became a Research Chemist from 2013-2018. In 2018, John joined the University of Florida and has published over 60 journal articles and over 20 focusing on PFAS.
</blockquote>
<blockquote>
Presenter: Kevin J. McHale, Ph.D. (Senior LC-MS Application Scientist, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Kevin is a Senior LC-MS Applications Scientist with Thermo Fisher Scientific. Starting his professional career in 1994 with DuPont Merck, Kevin helped implement “walk-up” LC-MS systems supporting synthetic medicinal chemists. In 1997, Kevin left to pursue his Ph.D. in Analytical Chemistry under the direction of Professor Rick Yost at the University of Florida. Kevin’s research focus was studying ion trap fundamentals and developing nano LC-MS/MS techniques. Upon completion in 2002, Kevin joined Thermo Fisher Scientific as an LC-MS Marketing Specialist supporting the Thermo Scientific™ TSQ Quantum™ triple quadrupole mass spectrometer. With over 21 years at Thermo Fisher, Kevin presently specializes in developing methodology for quantitative LC-MS analyses of small organic compounds on the Thermo Scientific™ TSQ and Thermo Scientific™ Orbitrap Exploris™ mass spectrometer product lines.
</blockquote>

Thermo Scientific: Expanding the scope of PFAS screening and quantitation through targeted acquisition – water analysis and beyond

Expanding the scope of PFAS screening and quantitation through targeted acquisition – water analysis and beyond

Explore the range of sample types examined for routine PFAS detection and quantification.

Expanding the scope of PFAS screening and quantitation

<h5>Solving Problems that Matter: Risk Mitigation in the Pharma QC Laboratory</h5>
Expert Insights 3-Part Webinar Series: Risk Assessment, Control Strategies, and Intuitive Innovation to Improve Data Quality, Data Integrity and Lab Productivity. 
Pharma QC labs are facing increasing pressure on the cost of quality while maintaining compliance and assuring patient safety. From the harmonization of USP &lt;621&gt; to Empower™ workflows supporting data integrity to improving method transfer outcomes, you will learn from subject matter experts how to reduce errors and mitigate risk for reproducible data and enhanced productivity. 
Who should attend
<ul>
<li>Pharma QC Lab directors, managers and senior scientists with a drive to reduce errors, improve lab productivity and enhance data quality &amp; integrity.</li>
</ul>
<h3>PART 2 l Improving Method Transfer Outcomes with Intuitive Innovation</h3>
<ul>
<li>Wednesday, August 16th, 11:30-12:30 ET</li>
</ul>
Your LC systems need to support both legacy and new methods that can be operated repeatably anywhere in the world while meeting regulatory requirements. These requirements can also place a large burden on your analysts, but failing to perform necessary tasks could put your organization at risk.
This webinar will introduce our latest HPLC innovation – the Alliance iS HPLC System – that features improved enhanced temperature control to match global needs. Additional features include our intelligent method translator app (iMTA), method matching app, system audit trail and automated column history tracking.
<blockquote>
Presenter: Lise Gauthier (Principal Scientist, Waters Corproation)
</blockquote>
<blockquote>
Lise Gauthier is Principal Scientist within the QA/QC Business Strategy group at Waters Corporation in Milford, MA. Prior to joining Waters in 2014, Lise worked as a scientist as Astra Zeneca for 20 years holding positions of increasing responsibility within Quality Assurance and Drug Discovery. Her current role at Waters includes system validation and evaluation of competitive systems.
</blockquote>

Waters Corporation:  Improving Method Transfer Outcomes with Intuitive Innovation

 Improving Method Transfer Outcomes with Intuitive Innovation

Latest HPLC innovation – the Alliance iS HPLC System – that features improved enhanced temperature control to match global needs.

Method Transfer Outcomes with Intuitive Innovation

Dive into the world of biopharma analysis with us as we cover the essential aspects of oligonucleotides, a group of rapidly advancing drugs that offers promising treatments and holds great potential for personalized medicines.
We will showcase state-of-the-art solutions that support the entire workflow employed by Contract Drug Manufacturing Organizations (CDMOs), from R&amp;D to validation and manufacturing. Get valuable insights into biopharmaceutical drug development and delve into the capabilities of our solutions, including our Nexera XS inert system, LCMS-9050 QTOF, and the latest LabSolutions Insight Biologics software.
Learning Objectives:
<ul>
<li>Introduction to the crucial aspects of oligonucleotides as therapeutics
</li>
<li>Understand the increasingly important role of LCMS in biopharma for manufacturing, QC, and confirmation
</li>
<li>Explore Shimadzu’s latest hardware and software solutions
</li>
</ul>
<blockquote>
Presenter: Neil Loftus (General Manager, Mass Spectrometry Business Unit (Overseas), Shimadzu Corporation)
</blockquote>
<blockquote>
Neil Loftus is an expert in developing new mass spectrometry technologies and innovative data processing workflows to solve complex analytical problems. As the General Manager of the Mass Spectrometry Business Unit (Overseas) at Shimadzu Corporation, he brings a wealth of experience to his current role. Neil&#39;s professional journey began at the London Hospital Medical College, where he focused on academic and pharmaceutical research applications in metabolism and pharmacokinetics. He then continued his work in clinical quantitative bioanalysis and metabolite identification in an industrial setting before transitioning into mass spectrometry. Throughout Neil’s career, he has remained deeply involved in mass spectrometry research and development. His contributions include publishing scientific papers on pharmaceutical metabolite identification and biomarker research, as well as generating new solutions to change the way we think about data and solve problems that matter.
</blockquote>
<blockquote>
Presenter: Max Kosok (Senior Product Specialist (LCMS), Shimadzu (Asia Pacific) Pte Ltd)
</blockquote>
<blockquote>
With more than 14 years of experience, Dr. Kosok is a passionate expert in mass spectrometry. He has received is PhD from National University of Singapore in Biochemistry doing proteomics research on triple negative breast cancer by high resolution LCMS. In 2020, he joined Shimadzu to deliver end-to-end LCMS application solutions for customers. In his current role as a Product Specialist for LCMS and previously as an application chemist, Dr. Kosok has worked with various pharma and biopharma customers. He has supported a multitude of applications from impurity analysis to biomolecule characterization, particularly on Shimadzu’s LCMS QTOF technology.
</blockquote>

Shimadzu: Towards the Future of Biopharma: Insights into Oligonucleotide Therapeutics

Towards the Future of Biopharma: Insights into Oligonucleotide Therapeutics

State-of-the-art solutions that support the entire workflow employed by Contract Drug Manufacturing Organizations (CDMOs).

Insights into Oligonucleotide Therapeutics

In this work, we present novel, automated, and integrated software to support these workflows using LC HRAM MS instruments.
Purity and sequencing data are presented for a multitude of oligos including antisense, aptamer, and long synthetic samples.
<blockquote>
Presenter: Shashank Jain, PhD (Mass Spec product specialist, New England, Agilent Technologies, Inc.)
</blockquote>

Agilent Technologies: Relieve the Pressure of Oligo Characterization by Implementing Automated Workflows

Relieve the Pressure of Oligo Characterization by Implementing Automated Workflows

Novel, automated, and integrated software to support these workflows using LC HRAM MS instruments.

Oligo Characterization by Implementing Automated Workflows

This series is comprised of four different, dissolution focused, lightning talks.
Sessions have been optimized to give you the information you need in a flash - less than 30 minutes per session. Topics include tips for preventing failures, improving efficiency, and more!
​​​​​This talk focuses on key aspects of the dissolution workflow that can be accelerated to produce data faster and reduce overall time between tests.
<blockquote>
Presenter: Ken Boda (Dissolution Product Specialist, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Ken joined Varian (now Agilent) in 2005 as an Applications Engineer, is now a Product Specialist. Prior to working with Agilent, he worked in pharma specialized in dissolution testing and method development. He works with customers in determining the best systems for their needs and optimizing their work flows. He has also helped educate customers on dissolution science through webinars, the Dissolution Discussion Group, LinkedIn, etc.
</blockquote>

Agilent Technologies: How to Improve Efficiency by Accelerating Your Dissolution Testing

How to Improve Efficiency by Accelerating Your Dissolution Testing

Key aspects of the dissolution workflow that can be accelerated to produce data faster and reduce overall time between tests.

Improve Efficiency by Accelerating Your Dissolution Testing

Key Learning Points:
Discover the methodology for effectively evaluating and screening the most suitable HPLC column
Acquire comprehensive knowledge regarding the critical parameters crucial for column selectivity and evaluating a HPLC phase
This presentation will include a parallel comparison of Core-shell and fully porous columns
Who Should Attend:
<ul>
<li>Any HPLC, or Clinical users who are interested in learning tips and tricks in order to pick the right column</li>
</ul>
<blockquote>
Presenter: Shahana Huq (Senior Application Scientist, Phenomenex)
</blockquote>
<blockquote>
Shahana W. Huq is a Senior Application Scientist focusing on emerging technologies and solutions within Clinical Research and Sample Preparation, at the Phenomenex Applications Laboratory since the year 2000. She holds an MS in Biochemistry from California State University, Los Angeles. Her work involves experimental design, analytical method development, optimization, and troubleshooting. Furthermore, she has extensive expertise in R&amp;D product innovation and application development, as well as hands-on experience in sample preparation and LC-MS/MS. Shahana’s drive, and vision of the clinical field has motivated her to participate in various scientific publications and even as a coauthor of Phenomenex patent on sample preparation products (2006). Currently, Shahana works closely with global customers in the clinical research industry, providing technical support and consultation services as well as onsite seminars and webinars to promote peer development.
</blockquote>

Phenomonex: Column Selectivity Screening for Vitamin K Compounds

Column Selectivity Screening for Vitamin K Compounds

Methodology for effectively evaluating and screening the most suitable HPLC column.

Polar pesticides are a few of the most challenging compounds to be analyzed by analytical methods.
Their extensive use in agriculture has raised safety concerns around the world and the routine analysis of these compounds has become a requirement for many food laboratories. A growing list of analytes, complex matrices, proper retention and separation of these compounds, and reproducibility are just a few of the challenges testing labs have to deal with. 
Key Learning Points:
Overcome critical challenges in polar pesticides analysis and throughput.
Develop and optimize a robust method for cationic and anionic pesticides.
Learn new advances in column selectivity and MS for optimized separation of polar pesticides.
Who Should Attend:
Any LC users who want to learn about a faster yet robust analysis of polar pesticides or any lab managers who would need consolidation of anionic and cationic pesticides on a single column.
<blockquote>
Presenter: Zara Jalali (Applications Scientist, Phenomenex)
</blockquote>
<blockquote>
Zara did her MSc. in chemical engineering/separation sciences during which she organized many research conferences, and she is passionate about science and technology. She has been working in the field of analytical chemistry for over 15 years, as a toxicologist, forensic scientist, application scientist and lab director. She has extensive experience in the clinical, environmental, forensic toxicology and cannabis industries and her content portfolio includes R&amp; D, Analytical method development &amp; optimization, sample preparation techniques, data analysis, validation, designing laboratory workflow and automation using chromatography, spectroscopy, and mass spectrometry techniques.
</blockquote>
<blockquote>
Zara is an expert using variety of analytical instruments such as GC, GC/MS, GC/MS/MS, HPLC, HPLC/MS/MS and ICP/MS. Zara joined Phenomenex in 2020, as an application scientist mainly focusing on environmental, food and cannabis applications. She has been helping the costumers and the team with finding new solutions for applied market while trying to improve analytical solutions for this dynamic market.
</blockquote>
<blockquote>
Presenter: Dr. Ramkumar Dhandapani
</blockquote>
<blockquote>
Dr. Ramkumar Dhandapani has been in the chromatography industry for over 20 years with hands on and troubleshooting experience.
</blockquote>
<blockquote>
He has earnt a Masters and Ph.D degree in Analytical chemistry from Seton Hall University with specialization in Microextractions, Multidimensional Chromatography and Tandem Mass Specs techniques. He has developed and validated several regulatory compliant methods in Pharmaceutical, Food, Fuels and Environmental industry as well as incorporated method improvement and troubleshooting across a range of separation techniques.
</blockquote>
<blockquote>
Dr. Dhandapani joined Phenomenex in August of 2014 and he serves as a Senior Product Manager at Phenomenex. In addition to managing the product line, Dr. Dhandapani presents on innovations in separation science at various chromatography conference.
</blockquote>

Phenomenex: Fast and Robust Analysis of Anionic and Cationic Pesticides on a Single Column

Fast and Robust Analysis of Anionic and Cationic Pesticides on a Single Column

Critical challenges in polar pesticides analysis and throughput.

Fast and Robust Analysis of Anionic and Cationic Pesticides

Are you using Chromeleon CDS but don’t feel like an expert just yet? Are you interested in a CDS that is intuitive and user-friendly? Whether you’re a day-to-day user or just curious about a new CDS, this is the webinar for you!
What this session covers:
<ul>
<li>Fundamentals of Chromeleon CDS</li>
<li>How to create custom reports</li>
<li>New features in Chromeleon 7.3.2 CDS</li>
<li>Benefits of upgrading from workstation to enterprise with the Ardia Platform</li>
</ul>
<blockquote>
Presenter: Seth Sheridan (Product Specialist III, Enterprise CDS, Americas, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Seth is an Enterprise CDS technical specialist who has supported Thermo Fisher’s Chromeleon software for over 3 years. Prior to this, he used Chromeleon and other CDS systems in labs at DuPont, DOW, and Eurofins. He holds a B.S. in Chemistry and Biochemistry and enjoys working closely with chromatographers to solve their software issues and improve their processes.
</blockquote>

Thermo Scientific: Learn the secrets of Chromeleon CDS: Expert advice and tips

Learn the secrets of Chromeleon CDS: Expert advice and tips

Fundamentals of Chromeleon CDS. How to create custom reports. New features in Chromeleon 7.3.2 CDS. Benefits of upgrading from workstation to enterprise.