Streamlining PFAS Analysis with Automated Sample Preparation and LC/MS

PFAS testing laboratories are being asked to do more than ever before. As regulatory requirements evolve and target analyte lists expand, analysts across environmental, food, and materials testing laboratories must deliver reliable trace-level PFAS measurements in increasingly complex applications. In this seven-part mini webinar series, we explore a range of solutions for trace-level PFAS determination, including Feed Injection and large-volume injection techniques, automated sample preparation, direct injection workflows, SPE strategies, thermal desorption, and complementary LC/MS/MS and GC/MS approaches. Each webinar addresses a different aspect of PFAS analysis, providing practical insights into workflow design, method performance, and laboratory productivity.

Session 2: Streamlining PFAS Analysis with Automated Sample Preparation and LC/MS

Discover how automated sample preparation can simplify PFAS analysis in concrete and other solid environmental matrices. This webinar showcases a streamlined workflow using the CTC PAL3 RTC autosampler coupled to Agilent LC/MS/MS, delivering reliable trace-level quantitation, improved reproducibility, and increased laboratory throughput. Solid matrices such as concrete can make PFAS analysis challenging, particularly when laboratories need reliable trace-level results.

In this mini webinar, discover how to:

• Automate key steps in PFAS sample preparation.
• Improve reproducibility and consistency.
• Combine automated preparation with sensitive LC/MS/MS detection.

Presenter: Christian Hegmanns (Application Specialist LC/MS, Agilent Technologies)

Christian Hegmanns is a state-certified food chemist and works at Agilent as an LC/MS application specialist. With over 10 years of experience in the field of instrumental analysis, Christian develops customer-oriented solutions for a variety of applications with a focus on food analysis.

Presenter: Melanie Behling (Service Tech, Agilent Technologies)

Melanie Behling is a certified chemical laboratory technician specialising in analytical chemistry, with experience spanning academia, public laboratories, and industry. Throughout her career, she has worked extensively with HPLC, UHPLC, LC/MS, GC/MS, and GC-FID systems, gaining expertise in method development, instrumental analysis, and laboratory operations. Since joining Agilent in September 2025, she has been supporting the EMEAI team, with a particular focus on LC/MS and GC/MS technologies, helping customers and colleagues achieve successful analytical outcomes. Outside of work, she enjoys hiking, spending time with family and friends, and volunteering in her local community.