Characterization and Quantification of Synthetic Oligonucleotides Using HRAM and QQQ

Mass spectrometry plays a vital role in the measurement and characterization of synthetic DNA and RNA oligonucleotides (oligos), which are used widely in molecular biology and in the development of therapeutics.

This webinar will highlight:

• (1) the quantitative analysis of oligos, both by QQQ and HRAM technologies, to achieve the best combination of sensitivity and speed,
• (2) impurities determinations using HRAM, multiple analysis techniques, and purpose-built software, and
• (3) high-throughput methods that enable the acquisition, analysis, and purity review of over 5,000 samples a day.

Join us to push the speed, sensitivity, and dynamic range of oligo measurements to new heights.

For Research Use Only. Not for use in diagnostic procedures.

Presenter: Peter Rye, PhD (LCMS Applications Scientist, Agilent Technologies, Inc.)

Peter is a pre-sales Application Engineer with Agilent Technologies. He has been with Agilent for 10 years developing LC, RapidFire, and mass spec methods on a wide range of molecules. Prior to Agilent, Peter worked in analytical development groups for BioTove and BIOCIUS, the original companies that developed the RapidFire platform. In his spare time, you can find Peter relaxing with his wife and kids in Beverly Massachusetts, trying to fix the many problems with his home, or staying active outdoors.