Targeted Proteomics: Tiny Samples, Big Accuracy: Large-Panel Targeted Proteomics with 6495D LC/TQ

Quantitative analysis of low amount samples such as single cell proteome requires highly sensitive instruments. Targeted quantification analysis using Evosep One, Newomics ion source and Agilent 6495D Triple Quadrupole LC/MS significantly increased method sensitivity. Enhanced acquisition software on 6495D LC/TQ enable 10K targeted transitions from over 1000 peptides in a method.

These improvements together greatly increase method selectivity, sensitivity and throughput for proteomic quantification in tiny samples.

Presenter: Linfeng Wu (LC/MS Application Scientist, Agilent)

Dr. Linfeng Wu received her Ph.D. in 2007 at University of Connecticut for Biomedical Sciences. After a post-doc training in Dr. Michael Snyder’s group at Stanford University, she worked as a research scientist in biotech industry. Dr. Wu joined Agilent in 2015 as an application scientist, focusing on LC/MS-based analysis for protein, proteomics and small molecule analysis.