Optimized Reversed Phase Analysis of Semaglutide

ZÁZNAM | Proběhlo St, 10.9.2025
Prozkoumejte vývoj metody LC pro agonisty GLP-1, jako je semaglutid. Seznamte se s tipy pro gradient, výběrem kolon a poznatky ze studií degradace s Lucií Geis Asteggiante.
Phenomenex: Optimized Reversed Phase Analysis of Semaglutide
Phenomenex: Optimized Reversed Phase Analysis of Semaglutide

Overview

  • During this presention, we will review the following:
  • What are GLP-1 receptor agonists
  • What challenges do they present to analysts
  • Semaglutide and related substances analysis
  • Semaglutide forced degradation studies

Key Learning Points

  • Identify key considerations when using reversed-phase chromatography for peptide analysis.
  • Learn about mobile phase and column considerations in method development
  • Explore strategies for optimizing gradients to account for sample complexity.

Who Should Attend

  • Any analytical ccientists involved with GLP-1 receptor agonists analysis

Speaker: Lucia Geis Asteggiante (Senior Technical Specialist, Phenomenex)

Lucia is a Senior Technical Specialist that has recently joined Phenomenex’s Global Technical Team. She has a broad experience in the field of Analytical Chemistry with a particular focus on LC chromatography coupled with mass spectrometry. Lucia comes from a strong academic and regulatory background with experiences ranging from method development and analysis of small molecules to large protein complexes. She gained her Ph.D. at the University of Maryland - College Park, USA and did her post-doctoral work at the University of Oxford, UK. During her time as a researcher, she has authored/co-authored 23 scientific publications and 2 book chapters.

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