4D-Lipidomics: Searching for the Fountain of Youth

To confidently characterize complex lipidomes of whole organisms, researchers require comprehensive MS/MS coverage of detected lipids. Compared to conventional analyses, the timsTOF Pro, used with Parallel Accumulation Serial Fragmentation (PASEF) acquisition mode, acquires MS/MS spectra with uncompromised sensitivity and resolution.

This webinar will demonstrate Bruker’s fully integrated lipidomics workflow in MetaboScape and outline how novel 4D-lipidomics tools has been used to gain a better understanding of how a sphingolipid mutation in the C. elegans relates to an increased lifespan – or in other words, the fountain of youth.

Attend the webinars to discover how to:

• Increase confidence in lipid annotation using rule-based annotation to reduce false positives
• Increase the number of MS/MS in a single run to allow for a higher level of chain composition annotation
• Automatically record reproducible CCS for all lipids within a sample to further add confidence
• See how new visualisation tools, including Kendrick mass defect plots, can save time and simplify your research

Presenter: Dr. Michael Witting (Scientist, Research Unit Analytical BioGeoChemistry, Helmholtz Zentrum München)

Presenter: Dr. Ansgar Korf (Software Engineer, Bruker Daltonik GmbH)