Photothermal AFM-IR Spectroscopy and Imaging for Life Science

Photothermal AFM-IR can provide nanoscale chemical information with highly resolved IR spectra, that directly correlate to FTIR transmission spectroscopy. This webinar covers numerous AFM-IR applications in the field of life sciences, illustrating broad applicability for samples from tissue to single protein fibrils. The speaker also discusses issues, challenges, and potentials of correlative measurements.

Some of the samples and applications presented include:

• Lipids bodies stored in microorganisms
• Abnormal accumulations in kidney biopsy
• Penetration of nanocarriers in tissue or model cell lines
• Protein nano-assemblies structures

The speaker discusses the new experimental approaches developed to solve problems encountered during these studies, and the efforts to overcome technical constraints imposed by the system itself, such as:

• Configuration of illumination
• Sensitivity
• Soft-sample damage