Improving Metabolite Identification During Imaging by Desorption Electrospray Ionization (DESI) Mass Spectrometry

Application Note Data Independent HDMSE High Throughput Drug Library Screening Using the DESI XS Source Lisa Reid, Mark Towers, Michael McCullagh, I.D. Wilson, Robert S. Plumb, Joanne Connolly Waters Corporation Abstract Desorption electrospray ionization (DESI) coupled to an ion mobility…

[ APPLICATION NOTEBOOK ] MS IMAGING AND AMBIENT IONIZATION-MS FOR METABOLOMICS AND LIPIDOMICS 1 This notebook is an excerpt from the larger Waters’ Application Notebook on Metabolomics and Lipidomics #720005245EN TABLE OF CONTENTS 3 Introduction 4 Biomarker Discovery Directly from…

COLLISION CROSS SECTION ENABLED DESI ION MOBILITY MASS SPECTROMETRY IMAGING Anthony J. Midey, Hernando J. Olivos, and Bindesh Shrestha Waters Corp., Beverly, MA INTRODUCTION Mass spectrometry imaging (MSI) determines the localization of compounds on samples, including tissue sections and drug…

[ APPLICATION NOTEBOOK ] STRUCTURAL ELUCIDATION 1 This notebook is an excerpt from the larger Waters’ Application Notebook on Metabolomics and Lipidomics #720005245EN TABLE OF CONTENTS 3 Introduction 4 Traditional Herbal Medicine Structural Elucidation using SYNAPT HDMS with Time-Aligned Parallel…